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June 06-07, 2019 | London, UK
2nd International Conference on
Tissue Science and Molecular Biology,
Stem Cells & Separation Techniques
Joint Event
Biomedical Research (An International Journal of Medical Sciences) | ISSN: 0976-1683 Volume 30
Similar processes affect cancer and atherosclerosis
Abdallah Alameddine
University of Massachusetts, USA
Cancer and Cardiovascular diseases are the leading
causes of mortality worldwide with increasing new
cases every year. Both illnesses are characterized by
uncontrolled cellular proliferation and progressive growth
and based on the recent advent in cell biology and cancer
metabolism in addition to epidemiologic observations,
the critical roles of immune system have been revealed
in patients with those conditions. We have thus learned
that the inflammatory response in arteries does not
differ from that in cancer tissue or from those in chronic
inflammatory states. In this presentation, we shed light
on the characteristic parallels between the neoplastic
response and atherosclerosis. As we highlight, ostensibly
both processes are interlinked by an inflammatory
response as has been predicted by Rudolph Virchow who
first made the connection between inflammation and
cancer over 150 years ago. Important for our discussion,
an example of epidemiologic data suggesting increased
cancer rates in adults after cardiac interventions as compared
with the state of Massachusetts general population will be
underscored. Based on these remarks, strategies for reducing
cancer risk may be implemented that could positively affect
outcome in cardiovascular patients and the screening process
for asymptomatic malignancies.
e:
Biomed Res, Volume 30
ISSN: 0976-1683