nutrition-world-2017-scientifictracks-abstracts

6 / 25

alliedacademies
Insights Nutr Metab 2017
Volume 1 Issue 3 Nutrition World 2017
Notes:
Page 24
September 11-12, 2017 Edinburgh, Scotland
15 th World Congress on
Advances in Nutrition, Food Science & Technology
Nutrition and stress prevention programs in
livestock/animal production: From vitamins
to vitagenes
Peter F Surai1,2 and Vladimir I Fisinin3
1Feed-Food Ltd, UK
2Moscow State Academy of Veterinary Medicine and Biotechnology,
Russia
3All-Russian Institute of Poultry Husbandry, Russia
C ommercial livestock/animal production is associated
with four major types of stresses, including
environmental, technological, nutritional and internal
stresses, affecting productive and reproductive
performance of animals and their health status. It has
been suggested that at the molecular level most stresses
are associated with overproduction of free radicals and
oxidative stress. Therefore, the development of the
effective antioxidant solutions to decrease negative
consequences of commercially-relevant stresses is
an important task for animal/poultry scientists. One of
such approaches is based on possibilities of modulation
of vitagenes, a family of genes responsible for animal
adaptation to stress. In fact, the vitagene network includes
heat shock proteins (HSPs), thioredoxin system, sirtuins
and superoxide dismutases (SODs) and plays a regulatory
role in most important cellular processes in stress
conditions. Indeed, HSPs, including heme oxygenase-1
and HSP70, are responsible for protein homeostasis
in stress conditions, while the thioredoxin system is
the major player in maintaining redox status of the cell
involved in protein and DNA synthesis and repair as well
as in regulation of expression of many important genes.
Furthermore, sirtuins regulate the biological functions
of various molecules post-translationally by removing
acetyl groups from protein substrates ranging from
histones to transcription factors and orchestrate cellular
stress response by maintenance of genome integrity and
protein stability. Finally, SODs belong to the first level of
antioxidant defence preventing lipid and protein oxidation
at the very early stages. All the vitagenes operate in
concert building a reliable system of stress detection
and adequate response and are key elements in stress
adaptation. Our studies clearly showed that supplying
vitagene-regulating nutrients (carnitine, betaine, vitamin
E, etc.) via drinking water could significantly improve
adaptive ability of poultry/farm animals to commercially-
relevant stresses and prevent decrease in their productive
and reproductive performance.
Peter F Surai is supported by a grant of the Government
of Russian Federation, Contract No. 14.W03.31.0013
Biography
Peter F Surai has his expertise in Animal and Human Nutrition and published a
number of papers as well as two books (“Natural Antioxidants in Avian Nutrition
and Reproduction”, 2002; and “Selenium in Nutrition and Health”, 2006) which
became textbooks for animal nutritionists. His recent research is devoted to
the development of effective strategies to fight commercially relevant stresses
in livestock/animal production. He successfully transferred vitagene concept
from Medical Sciences to Animal and Poultry Science and developed stress-
prevention programs based on supplying vitagene-regulating nutrients to farm
animals via drinking water. He held Honorary Professorships in Nutritional
Biochemistry at various universities in the UK, Hungary, Bulgaria and Ukraine,
and became a Foreign Member of Russian Academy of Sciences. For the
last 15 years he has been lecturing all over the world visiting more than 70
countries.
Peter F Surai et al., Insights Nutr Metab 2017