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June 06-07, 2019 | London, UK
2
nd
International Conference on
Tissue Science and Molecular Biology,
Stem Cells & Separation Techniques
Joint Event
Biomedical Research (An International Journal of Medical Sciences) | ISSN: 0976-1683 Volume 30
The combined use of fat graft enriched with stromal vascular fraction cells and
platelet-rich plasma in the treatment of breast soft tissue defect
Pietro Gentile
University of Rome Tor Vergata, Italy
T
he use of autologous fat grafting is ideal in breast
reconstruction. However, published data on long-term
outcomes and instrumental results of fat grafting to the
breast are lacking. The purpose of this study was to review
the authors’ experience of fat grafting, evaluating the effects
related to the use of enhanced stromal vascular fraction
(e-SVF) and fat grafting with platelet-rich plasma (PRP) in
the maintenance of fat volume in breast reconstruction,
comparing the results with a control group. Twenty-three
patients aged 19–60 years affected by breast soft tissue
defects were analyzed at the Plastic and Reconstructive
Department of theUniversity of Rome Tor Vergata. 10patients
were treated with SVF-enhanced autologous fat grafts and 13
patients were treated with fat grafting mixed with platelet-
rich plasma. The patients in the control group (n=10) were
treated with centrifuged fat grafting injection according
to Coleman’s procedure. The patients treated with SVF-
enhanced autologous fat grafts showed a 63% maintenance
of the contour restoring and of three-dimensional volume
after 1 year compared with the patients of the control
group treated with centrifuged fat graft, who showed a 39%
maintenance. In those patients who were treated with fat
grafting and PRP, we observed a 69%maintenance of contour
restoring and of three-dimensional volume after 1 year.
As reported, the use of either e-SVF or PRP mixed with fat
grafting produced an improvement in maintenance of breast
volume in patients affected by breast soft tissue defect.
e
:
pietrogentile2004@libero.itBiomed Res, Volume 30
ISSN: 0976-1683