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Journal of Dermatology Research and Skin Care | Volume 2

May 14-15, 2018 | Montreal, Canada

Spring Dermatology &

Skin Care Expo Conference

ifferent sets of molecules are released from multiple

stem cell types in any given tissue, and are naturally

packaged into a “smart liposome” called the exosome,

which has highly evolved protection, targeting, and delivery

characteristics for the molecules. Most of the healing

properties of stem cells derive from these molecules.

Chronological aging, and many environmental factors during

the aging process, lead to diminished stem cell function

throughout our bodies, and the quantity and quality of the

stem cell released molecules (SRM) that nourish the hair and

skin are reduced, leading to disruption of homeostasis and

a chronic para-inflammatory state. This unhealthy state of

the skin and hair forms wrinkles, sags, and loss of elasticity,

and follicular miniaturization. Homeostatic renormalization

can be achieved by returning the normal SRM to the aged

skin and scalp, and is best achieved using multiple types

of adult stem cells normally found in the particular tissue.

The collection of molecules from multiple stem cells types,

as opposed to a single molecule traditionally used in

therapeutic development is called a “systems therapeutic.”

The systems therapeutic induces emergent, collective

efficacy that is vastly greater than that of using one or a few

molecules, and when developed using endogenous human

molecules and exosomes, produces a superior therapeutic

with optimal safety and efficacy profiles. Examples of the

therapeutic value of S2RM technology for a number of skin

(e.g. acne) and hair conditions (e.g. alopecia) will be shown.

Speaker Biography

Greg Maguire is a former Professor of Neuroscience and Ophthalmology at the

University of California, San Diego School of Medicine. He was a Fulbright-Fogarty

Fellow at the National Institutes of Health USA, and his research has been supported by

the NIH and NSF, as well as numerous private foundations. With over 100 publications

emanating from his work at UC Berkeley and UCSD, he recently established two biotech

companies, where his patentedS2RM technology is used to treat neurodegenerative

and skin diseases, and conditions.

Homeostatic renormalization of hair and skin tissue using adult stem cell S2RM technology

Greg Maguire

University of California, USA