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academies
Journal of Dermatology Research and Skin Care | Volume 2
May 14-15, 2018 | Montreal, Canada
Spring Dermatology &
Skin Care Expo Conference
T
he author wants to present a mathematical base
approaches for the simulation of thermal therapy. This
method is useful in surgical procedures for selective removal
of target in the biological multilayered tissues. In practice the
process must be done without overheating the healthy tissue
by controlling a source heating energy power and surface
cooling temperature. One of the objectives of hyperthermia
is to raise the temperature of the skin diseased to a
therapeutic value, and then thermally destroy the disease.
Here, hewants to describe how the practical surgical problem
is modeled by a multilayered optimal control problem for
some biological composite tissues, consisting of skin, fat,
muscle and tumor. Mathematically, we consider bio-heat
transfer equation with practical boundary conditions to
attain the desired temperature at the specific final time. The
microwave, the ultrasound, and the laser are popular power
heating apparatus used to deposite heat for treating the
tumor in the deep biological body. In this approach, the laser
heat source induced by conducting heating probe inserted
at the tumors site. We control the tumor temperature inside
the composite tissue, by controlling the laser heat source
while the heat source is unknown and decomposed in each
preassigned time period discretization. Problems are solved
using strongly continuous semi-groups theory and Laplace
transformation. A solution matches at the adjacent layers
interfaces. Strongly continuous semi-groups theory used
to compute the optimal control functional at the specific
depth inside biological body. Mathematical simulations
for a thermal therapy in the presence of internal tumor
and external laser heat source are given to investigate the
method’s efficiency. The proposed efficient method confirms
both practical and theoretical approaches.
Speaker Biography
Alaeddin Malek is currently working in private practice as a Tarbiat Modares University
Tehran, Iran. He is the author of Over Research Publications, in peer-reviewed journals.
e:
mala@modares.ac.irThermotherapy simulations in composite tissues
Alaeddin Malek
Tarbiat Modares University, Iran