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Journal of Dermatology Research and Skin Care | Volume 2
May 14-15, 2018 | Montreal, Canada
Spring Dermatology &
Skin Care Expo Conference
S
ubungual melanoma (SUM) is a rare variant of malignant
melanoma. It accounts for 3% of melanomas in the
Caucasian population. In Asians, however, the proportion of
SUM is higher and it accounts for up to approximately 10%
and 18% of cutaneous melanoma cases in Japan and Korea,
respectively. The mean age of onset of SUM is between 59
and 63 years old, and SUM is very rare in adolescents. The
18-year-old girl presented with a seven year history of black
discoloration of the nail plate and dark brown pigmentation
around the right thumb nail. Initially, a longitudinal
pigmented band was noted on the nail plate, which then
widened and darkened over time. Gradually, periungual black
discoloration developed on the hyponychium and proximal
nail folds. In addition, splitting and fissuring of the nail
plate were noted. There was no family history of malignant
melanoma. Skin biopsy from the nail plate showed irregular
proliferation of spindle or round atypical melanocytes with
hyper chromatic nuclei at the dermal-epidermal junction
and pagetoid spreading of atypical melanocytes in the
epidermis. Immunohistochemical, atypical melanocytes
were positive for HMB-45. Based on these findings, the
patient was diagnosed with SUM
in situ
and transferred
to other hospital. The remaining lesions were completely
excised via wide local excision.
Speaker Biography
Hai-Jin Park is currently a Dermatology Professor in South Korea. He is the author of
over 55 publications, in peer-reviewed journals. He is a reviewer of multiple journals
with editorial positions in others. His expertize includes an interest in the dermatology
and dermatological diseases and melanoma disease.
e:
parkgreen24@gmail.comA case of subungual melanoma
in situ
in an 18-year-old girl presented with total melanonychia
Hai-Jin Park
Inje University, South Korea