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Journal of Dermatology Research and Skin Care | Volume 2

May 14-15, 2018 | Montreal, Canada

Spring Dermatology &

Skin Care Expo Conference

P

resent strategies for the treatment of pattern hair loss

are mainly focused on promoting cellular proliferation

and differentiation during the hair growth cycle. That means

recovering the normal physiology of the hair growth cycle.

This is why I used the termbio revitalization. Bio revitalization

the term we want to rebuild a physiological process leading

to continuous labile tissue reconstruction. Inmy presentation

she introduced her protocol and results with the use in

combination of PRP, carboxytherapy and alfatradiol 0.025%

capillary solution Supporters of platelet-rich plasma (PRP)

technology suggest that its benefits include an increase

in hard- and soft-tissue wound healing. In addition, the

role of PRP for the treatment of pattern hair loss has been

demonstrated in current reports, Injection of PRP has been

demonstrated to increase vascular structures around hair

follicles, also autologous PRP has been reported to induce the

proliferation of dermal papilla cells. Carboxytherapy consists

in the therapeutic use of carbon dioxide (CO

2

) in its sterile

gaseous state. At the vascular level, CO

2

increases vascular

tone and produces active microcirculatory vasodilatation.

CO

2

- induced vasodilatation, in addition, this promotes

Bohr’s effect, resulting in a higher tissue oxygenation and

neoangiogenesis. The tissue stretching during infusion

induces a subclinical inflammation, which triggers the

repair, and tissue regeneration processes that induce the

activation of macrophages, fibroblasts, and endothelial cells

that stimulate neovascularization and remodeling of the

extracellular matrix. Alfatradiol antagonizes the inhibitory

effect of testosterone proliferation and dihydrotestosterone

in the anagen hair follicles. Consequently, alfatradiol reduces

the dermal synthesis of dihydrotestosterone, inhibiting

the enzyme 5 reductase. With cutaneous administration,

effective concentrations of alfatradiol are obtained in the

skin and only a negligible amount is absorbed. She presents

her work during the last two years with the combination of

these methods with the following protocol over 41 patients,

20 women 21 men, PRP intradermic, injection, every four

weeks, then immediately carboxytherapy Intradermic, over

the whole area to be treated, giving a second pass. Alfatradiol

0.025% Capillary solution, as home maintenance is applied

in the evenings on clean and dry scalp. After the follow up

of the patients and the satisfaction from the therapeutical

result the author believes that these protocols have the

scientific support for one of the most important treatments

in the alopecia androgenic.

Speaker Biography

Pilar Reyes Agüero has studied at the University of Michoacan De San Nicholas De

Hidalgo. After she attended medical school she has studied in the Institute of Higher

Studies in Medicine at the University of El Conde in Mexico where she received two

masters one for Aesthetic Surgery and other for Aesthetic Medicine and longevity. She

has been practicing Aesthetic Surgery for over 15 years now. She is also a Professor in

the Specialty of Aesthetic Medicine and Longevity at the Institute of Superior Studies

in Medicine, Del Conde University in Mexico, where she teaches the students of the

Masters of Cosmetic Surgery. She has been a Member of the American Academy

of Cosmetic Surgery since 2004 as well as a Member of the College of Medical

Professionals in Aesthetic Surgery in Mexico since 2006. She is also a Director of the

International Union of Lipoplasty in Mexico-IU. Since 2012, she has been practicing PRP

(Platelet-Rich Plasma) for her own hair restoration protocol.

e:

dr_pil@hotmail.com

Successful hair restoration on bald patients with biorevitalization

Pilar Reyes Agüero

David Geffen School of Medicine, Mexico