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Journal of Nutrition and Human Health | Volume 3
May 23-24, 2019 | Vienna, Austria
Joint Event
2
nd
International Conference on
Gastroenterology and Digestive Disor
ders
17
th
International Conference on
Nutrition and Fitness
&
Effects of whey protein supplement in the elderly submitted to resistance training:
Systematic review and meta-analysis
Tamy Colonetti, Antonio Jose Grande, Karen Milton, Charlie Foster, Maria Cecilia Manenti Alexandre,
Maria Laura Rodrigues Uggioni
and
Maria Inês da Rosa
University of Extremo Sul Catarinense, Brazil
I
t is accepted resistance training promotes increased
muscle strength and skeletal muscle mass. In the aging
context, resistance training has a special importance
after 60 years old, when changes in body composition
are accelerated due to the aging process (Csapo &Alegre
2015). Whey protein is available as a dietary supplement
claimed for building muscle mass. Considering the rapid
rate of digestion, this supplement provides fast supply
of amino acids that can be absorbed by the muscles to
repair and rebuild muscle tissue (Chen
et al., 2014
). We
performed this systematic review to map the evidence
and analyze the effect of whey protein supplementation
in the elderly submitted to resistance training. We
performed a systematic review following the PRISMA–
statement guidelines (Liberati
et al.,
2009). The review
protocol is registered at PROSPERO (CRD42014014317).
A comprehensive search on Medline, LILACS, EMBASE
and the Cochrane Library for relevant publications was
conducted until August 2015. The terms used in the search
were: "Resistance Training"; “Whey protein”; “elderly”.
Results: A total of 632 studies were screened. Five studies
were included composing a sample of 391 patients. The
supplement whey protein was associated with higher
total protein ingestion 9.40 (95% CI 4.03 to 14.78), and
with an average change in plasma leucine concentration,
mean difference in plasma leucine concentration ranging
from 406μmol/L to 490μmol/L compared with the control
group
(p < 0.05, I² = 74%)
.The supplementation was also
associated with increased mixed muscle protein synthesis
1.26 (95% CI 0.46 to 2.07) compared to the control group.
Conclusion: We observed the use of whey protein in
older adults promotes an increase in total protein intake,
resulting in increased concentration of leucine and mixed
muscle protein synthesis rate.
e
:
tamycolonetti@hotmail.com