17 / 25
allied
academies
Page 50
Notes:
Journal of Nutrition and Human Health | Volume 3
May 23-24, 2019 | Vienna, Austria
Joint Event
2
nd
International Conference on
Gastroenterology and Digestive Disor
ders
17
th
International Conference on
Nutrition and Fitness
&
Non-alcoholic steatohepatitis before and after liver transplantation
Stefano Gitto
University of Florence, Italy
N
on-alcoholic steatohepatitis has become a leading
indication for liver transplantation in the western
countries. After transplant, both recurrent and de novo
non-alcoholic fatty liver disease can be usually diagnosed.
Nonetheless, dedicated surveillance programs for patients
with pre- or post-transplant non-alcoholic fatty liver
disease are not offered. Patients waiting for transplant for
non-alcoholic steatohepatitis show certain individualities
and would deserve targeted stratification of mortality
risk. Obesity, hyperlipidemia and diabetes mellitus can
be frequently diagnosed in the post-transplant period.
These conditions together with immunosuppressive
regimen, make transplant recipients a high-risk subgroup
for recurrent or de novo non-alcoholic fatty liver disease.
Onset of fatty liver disease after liver transplant has
a relevant impact on both morbidity and mortality. A
targeted stratification of neoplastic and cardiovascular
risk for patients with non-alcoholic steatohepatitis waiting
for transplant would be mandatory. In both pre- and
post-transplant period, non-alcoholic fatty liver disease
should be considered not only a liver disease but also
a cardiovascular risk factor. Patients within Transplant
Program, especially those with known metabolic risk
factors, should be followed with personalized diagnostic
and life-style interventions before and after transplant.
e
:
stefano.gitto@unifi.it