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Journal of Biomedical Research | Volume: 29
November 19-20, 2018 | Paris, France
Molecular Biology, Tissue Science and Regenerative Medicine
International Conference on
Joint Event
&
4
th
World Heart Congress
Tibetan patients with hepatic hydatidosis can tolerate hypoxic environment with no incident increase
of pulmonary hypertension - An echocardiograph study
Lixue Yin
Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, China
T
o evaluate the characteristics of right ventricular and
pulmonaryanatomicalstructure,functionandhemodynamics
of Tibetanpatientswithhepatichydatidosis living inhighplateau
using echocardiography. This prospective study is involved262
Tibetan patients diagnosed with hydatidosis from June 2016
to June 2017 in Shiqu and Seda areas (4178 meters above sea
level in Shiqu County and 3,878meters above sea level in Seda
County). Theanatomical structure, functionandhemodynamic
parameters of the right ventricle and pulmonary between the
Tibetan patients with hepatic echinococcosis and the high
plateau control group were compared.
In the hydatidosis group, there was no significant differences
in the detection rate of TR and PR (χ
2
=1.993, p=0.158 and
χ
2
=3.468, p=0.063, respectively). There was no significant
difference in the incidence of PAH (χ
2
=1.456, p=0.228) and also
no significant difference in the degree of PAH between the two
groups (38.93 ±4.60mmHg vs. 41.50 ±6.55mm, p>0.05). TheOR
value of PAH risk in patientswith hydatidosiswas 0.708 and the
95% CI was 0.317-1.582. There was no significant difference
in the detection rate of TR and PR between the subgroups of
hydatidosis and the plateau control group (χ
2
=2.323, p=0.508
and χ
2
=7.455, p=0.059, respectively). There was no significant
difference in the incidence of PAH (χ
2
=2.086, p=0.555) and also
no significant difference in the degree of PAH among the four
groups (F=0.738, p=0.535).
There was no significant effect on the incidence of pulmonary
hypertension and its pressure level in Tibetan patients,
suggesting that the pulmonary circulation system of Tibetan
might havea strong tolerance tohepatichydatidosis andhypoxic
environment simultaneously.
e:
yinlixue_cardiac@163.comMolecular Biology & Heart Congress 2018, Volume 29
DOI: 10.4066/biomedicalresearch-C8-023