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Journal of Biomedical Research | Volume: 29
November 19-20, 2018 | Paris, France
Molecular Biology, Tissue Science and Regenerative Medicine
International Conference on
Joint Event
&
4th World Heart Congress
Stress cardiomyopathy: Emerging concepts on diagnosis and management
Samer Ellahham
Cleveland clinic, UAE
Stress cardiomyopathy or takotsubo cardiomyopathy, is a
syndrome characterizedby transient regional left ventricular
dysfunction in theabsenceof significant coronaryarterydisease.
Possiblepathogenicmechanisms include catecholamineexcess,
microvascular dysfunction and multivessel coronary artery
spasm. Thediagnosis shouldbe suspected inadultswhopresent
with a suspected acute coronary syndrome when the clinical
manifestations are out of proportion to the degree of elevation
incardiacbiomarkers. Aphysical or emotional trigger is oftenbut
not always present.Wall motion abnormalities in patients with
stress cardiomyopathy are typically the apical type and atypical
variants includingmid-ventricular, basal, focal and global types.
The differential diagnosis of stress cardiomyopathy includes
acute coronary syndromes, coronary artery spasm, myocarditis
and pheochromocytoma. A high index of suspicion is key in the
diagnosis and management.
e:
Molecular Biology & Heart Congress 2018, Volume 29
DOI: 10.4066/biomedicalresearch-C8-023