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Page 59
allied
academies
Joint Event
February 21-22, 2019 | Paris, France
Microbiology & Applied
Microbiology
2
nd
International Conference on
World Congress on
Wound Care, Tissue Repair
and Regenerative Medicine
&
Journal of Trauma and Critical Care | Volume 3
Diversity, anti-quorum sensing and antimicrobial activities of endophytic actinobacteria isolated from
Mongolian plants
Oyunbileg Natsagdorj
1,2
, Davaapurev Bech Ochir
1
, Tsetseg Baljinova
2
, Yohei Iizaka
3
, Yojiro Anzai
3
, Fumio Kato
1
and
Batkhuu Javzan
1
1
National University of Mongolia, Mongolia
2
Mongolian Academy of Sciences, Mongolia
3
Toho University, Japan
W
ith the aim to find endophytic actinomycetes that
synthesize anti-quorum sensing (QS) compounds and
antimicrobials over 1000 strains were isolated from plants of
the desert and mountain areas of Mongolia. As a result, 11.9%
of our actinomycetes strains were found to possess the anti-
QS activity and 23.8% of the strains were active against gram
positive and negative bacteria. These strains also showed anti-
QS activity andantibacterial activitybybioautography assay. The
16 strains exhibiting the highest activity were analyzed by HPLC,
whichshowedthat all of themproduced flavonoidsandphenolic
compounds. These results suggest that those actinomycetes
could be potential candidates for the production of unique
biologically active compounds. Based on morphology and 16S
rRNA gene sequences analysis, 84 actinomycete strains were
assigned to the genera Streptomyces, Promicromonospora,
Pseudonocardia, Nocardia, Saccharothrix, Friedmanniella,
Micromonospora, Actinocatenispora and Geodermatophilus,
thelattertwogenerawereregisteredinMongoliaforthefirsttime.
e:
oyunbileg0515@gmail.comJ Trauma Crit Care, Volume 3
DOI: 10.4066/2591-7358-C1-003