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June 06-07, 2019 | London, UK

International Conference on

Tissue Science and Molecular Biology,

Stem Cells & Separation Techniques

Joint Event

Biomedical Research (An International Journal of Medical Sciences) | ISSN: 0976-1683 Volume 30

Separation of mixtures of chiral compounds by their distribution between different

phases

Emese Palovics

and

Fogassy E

Budapest University of Technology and Economics, Hungary

he distribution of mixtures of chiral compounds between

phases is characterized by the same diastereomeric like

behavior of the enantiomeric and diastereomeric mixtures.

The result of the separation is determined by the eutectic

composition of the enantiomeric mixtures of chiral molecules

which works as memory. The separation is influenced by the

nature of the phases and the time of phase-interactions.

Separation can be achieved without solvent by crystallization

from melt and by distillation. Separation from solvent can

be achieved by fractional crystallization, by crystallization

from solvate forming solvent, by extraction with supercritical

carbon dioxide or without crystallization using non-miscible

solvents. In each case, the result of the separation may

be influenced by taking into consideration of kinetic or

thermodynamic control.

Speaker Biography

Emese Palovics graduated from the University of Technology “Traian

Vuia” of Timisoara in 1990 as a chemical engineer. Since 1994, she has

been a scientific assistant at the Budapest University of Technology and

Economics in a research group of the Hungarian Academy of Sciences at

the department of organic chemical technology working on crown ethers

and organophosphorus compounds. Since 2004, she has been working

with Prof. Elemér Fogassy as senior research fellow in the field of optical

resolution. She earned her PhD in 2009, which studied structurally related

compounds with common skeleton in the resolution processes. She is the

co-author of 45 papers (the majority of which appeared in international

journals) and three patents.

Emese Palovics et al.

, Biomed Res, Volume 30

ISSN: 0976-1683