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Page 21

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June 06-07, 2019 | London, UK

2

nd

International Conference on

Tissue Science and Molecular Biology,

Stem Cells & Separation Techniques

Joint Event

Biomedical Research (An International Journal of Medical Sciences) | ISSN: 0976-1683 Volume 30

Coralline biomaterials for repair of brain damage

Danny Baranes

Ariel University, Israel

B

iomaterials can provide supportive microenvironment

for cell growth and exciting opportunities for tissue

regeneration. We found that biomaterials derived from the

calcium carbonate skeleton of corals in the crystalline form of

aragonite are protective and nurturing scaffolds for nervous

tissue growth and survival

in vitro

. Moreover, implantation

of coral skeleton into brain wounds generated following

traumatic brain injury in mice causes tissue restoration and

functional recovery. Implanted mice showed elevated level

of glial fibrillary acidic protein and nestin, markers of nervous

tissuegeneration,aswellasreducedanxiety,elevatedlearning

capacity and improved recovery from motor impairment,

compared to injured but not implanted mice. These results

place coralline scaffolds as a potential new mean to repair

damage in the central nervous system.

Speaker Biography

Danny Baranes has established his experience in neuroscience in

the lab of the Nobel laureate Dr. Eric Kandel at Columbia University,

New York, in the field of learning and memory. He was the first to use

coral skeletons scaffolds for brain tissue engineering. He publishes his

research in leading international scientific journals and conferences.

He is an associate professor and head of the department of molecular

biology at Ariel University, Israel.

e:

dannyb@ariel.com

Danny Baranes

, Biomed Res, Volume 30

ISSN: 0976-1683