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June 06-07, 2019 | London, UK
2
nd
International Conference on
Tissue Science and Molecular Biology,
Stem Cells & Separation Techniques
Joint Event
Biomedical Research (An International Journal of Medical Sciences) | ISSN: 0976-1683 Volume 30
Coralline biomaterials for repair of brain damage
Danny Baranes
Ariel University, Israel
B
iomaterials can provide supportive microenvironment
for cell growth and exciting opportunities for tissue
regeneration. We found that biomaterials derived from the
calcium carbonate skeleton of corals in the crystalline form of
aragonite are protective and nurturing scaffolds for nervous
tissue growth and survival
in vitro
. Moreover, implantation
of coral skeleton into brain wounds generated following
traumatic brain injury in mice causes tissue restoration and
functional recovery. Implanted mice showed elevated level
of glial fibrillary acidic protein and nestin, markers of nervous
tissuegeneration,aswellasreducedanxiety,elevatedlearning
capacity and improved recovery from motor impairment,
compared to injured but not implanted mice. These results
place coralline scaffolds as a potential new mean to repair
damage in the central nervous system.
Speaker Biography
Danny Baranes has established his experience in neuroscience in
the lab of the Nobel laureate Dr. Eric Kandel at Columbia University,
New York, in the field of learning and memory. He was the first to use
coral skeletons scaffolds for brain tissue engineering. He publishes his
research in leading international scientific journals and conferences.
He is an associate professor and head of the department of molecular
biology at Ariel University, Israel.
e:
dannyb@ariel.comDanny Baranes
, Biomed Res, Volume 30
ISSN: 0976-1683