23 / 27
Page 49
Notes:
allied
academies
October 22-23, 2018 | Frankfurt, Germany
International Conference on
Robo t i c s a n d A u t oma t i o n
B iomater ial s and Nanomater ial s
Joint Event
&
Journal of Biomedical Research | Volume 29
Advantages of chitosan – Curcumin nano system for multiple remedies
Michael Rajan
DOTE Campus Tamil Nadu State Council for Science and Technology, India
I
Chitosan a natural biopolymer possess interesting properties
towards drug delivery carrier system applications and
theranostics application. Chitosan based polyelectrolyte
complexes could be used as a promising drug delivery,
antibacterialandtheranosticsapplicationsnowadays.Curcumin
anatural therapeutic drugobtained fromturmeric is apromising
anticancer, antibacterial application in future. Natural Cancer
Drug Curcumin is a well-known dietary polyphenol derived
from the rhizomes of turmeric (Curcuma Longa), an Indian
spice, which is usually used in preparation of mustard and curry.
Three curcuminoids, namely curcumin, demethoxy curcumin,
and bisdemethoxy curcumin, are present in the natural extracts
of Curcuma Longa with curcumin as the principal constituent.
This yellow color spice has been used for thousands of years
as a traditional remedy. In Asian medicines, curcumin has been
used for the treatment of acne, psoriasis, dermatitis, and diaper
rash. It is a golden-yellow solid, with a molecular weight of 368
g mol-1 and a melting point of 183 °C. It is often used as a dye
owing to its vibrant colour. The aromatic rings are functionalized
with methoxy and hydroxy groups in an ortho position with
respect to one another. The aromatic rings are connected to
one another via a seven-carbon spacer that contains two α,
β-unsaturated carbonyl groups. As a result of this structure, a
beta-diketone and equilibrating keto-enol tautomeric forms
of curcumin are possible. While curcumin gained immense
attention as a medicinal drug in modern medical applications
only a fewdecades ago, it has beenused for hundreds of years in
some regions of the world. In Asia, especially in India and China,
turmeric has been used as a drug for more than two thousand
years. Ayurveda, an ancient medicinal systempracticed in India,
incorporated the use of natural herbs to treat various illnesses.
Amongst the commonly used herbs, turmeric was used most
abundantly due to the medicinal effects of curcumin. In the
traditional Ayurvedic approach, turmeric was crushed into
a paste for the treatment of eye infections, burns, bug bites,
and any skin related diseases. Furthermore, new mothers
in India are given a drink containing turmeric paste, honey,
ginger, and milk to drink daily following child birth. Turmeric
is also used in different forms to cure cough and respiratory
complications, along with dental diseases, flatulence, and
indigestion. Curcumin was also used as a medicine in ancient
Polynesian culture. It has been noted in historical documents
that the Polynesian people carried turmeric with them during
long voyages to Hawaii. Today, Hawaiians utilize curcumin for
various medicinal purposes. It is known to them as Olena.
e:
anjellojothi@gmail.comRobotics & Biomaterials 2018, Volume 29
DOI: 10.4066/biomedicalresearch-C6-017