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allied
academies
October 22-23, 2018 | Frankfurt, Germany
International Conference on
Robo t i c s a n d A u t oma t i o n
B iomater ial s and Nanomater ial s
Joint Event
&
Journal of Biomedical Research | Volume 29
New fiber reinforced composite material for custom-made craniofacial implants
Lazar MA
University of Medicine and Pharmacy, Romania
T
he aim of the present research was the elaboration and
the characterization of new fiber-reinforced composites
(FRCs) that will serve cranial bone reconstruction, particularly
in thecases of large bicortical calvarial defects. Four new
formulations of FRC were obtained using polymeric matrices
(combinations of monomers bisphenol A glycidylmethacrylate
(bis-GMA), urethane dimethacrylate (UDMA), triethylene
glycol dimethacrylate (TEGDMA), hydroxyethyl methacrylate
(HEMA)) and E-glass fibers (300g/mp). Every FRC contained
65% E-glass and 35% polymeric matrix. The newmaterials were
extensively characterized and tested for their chemical, phisical
and biological properties, using well estabished methods
(high performance liquid chromatography, scanning electron
microscopy, atomic force microscopy, X ray diffraction, flexural
and compression strength tests, citotoxicity and implantation
tests) and the best formulation was selected. The selected
material was used to produce personalized implants for the
reconstruction of critical size defects of rabbit calvaria. Local and
general impact upon animal health, quality of reconstruction,
bone and dura reaction to the material were investigated by
means of clinical, imaging and histological analysis. The results
of our research pointed out that the FRCs based on UDMA resin
reinforced with E-glass fibers could be an optimized alternative
to the similar nowadays available materials used for the
reconstruction of bone defects in the cranio-maxillofacial area.
e:
madilazar@yahoo.comRobotics & Biomaterials 2018, Volume 29
DOI: 10.4066/biomedicalresearch-C6-017