4 / 16
Page 34
allied
academies
Biol Med Case Rep 2017 | Volume 1 Issue 2
November 06-07, 2017 | New Orleans, USA
Nanomedicine & Healthcare
Global Meet on
N
anobioinformatics is a convergent field which integrates
the science of nanotechnology with bioinformatics.
Nanobioinformatics has the potential to solve problems
regarding high throughput genomics data, novel biomarker
discovery, complex biological systems, computer-aided drug
design (CADD), and nanobiology. Also, nanobioinformatics
can be used for devising and designing of different
nanosystems. In this context, for instance, bioinformatics
can efficiently facilitate identification of multiplexed probes
in a nanoparticle. Nano drugs are capable of cell targeting,
penetration, and controlled release. Today, the application
of nanobiotechnology in drug delivery systems is well-
known. Bioinformatics is an important predictive approach
for designing nano-transport systems for specific drugs.
Also, integration of the power of two chem/bioinformatic
techniques, molecular dynamics (MD) and docking, with
statistics can help prediction of the efficiency of drug loading
in nanoparticles. In addition, in the context of in-silico
drug design, nano-design through nanoscale simulation
and modeling requires cheminformatic and bioinformatic
techniques such as MD simulations, quantitative structure–
activity relationship (QSAR), molecular mechanics and
quantum mechanics. A growing number of publically
available databases such as nanoparticle ontology and
chemical entities of biological interest can be used to retrieve
required data for nanobioinformatic drug design. Altogether,
nanobioinformatics is a novel multidisciplinary field with
many potential capabilities in drug design and delivery
systems which may significantly accelerate the treatment
many deadly diseases including cancer.
Speaker Biography
Abbas is a student currently living in Tehran, Iran. He completed his diploma in biology
at the age of 18 years (2011) from Shahid Beheshti High School. Then, he obtained a
B.Sc. degree in Genetics from the Shahid Chamran University of Ahvaz in spring 2015.
Now, he is studying Masters of Biochemistry at the University of Kashan. His special
research interests range from Bioinformatics to Drug Design focusing on melanoma
and lung cancer. He is also interested in Epigenetics.
e:
abbas.salavaty@gmail.comApplication of nanobioinformatics in drug design and delivery systems
Abbas Salavaty
and
Mozhdeh Shahmoradi
University of Kashan, Iran