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Journal of Materials Science and Nanotechnology | Volume 3

October 07-08, 2019 | Frankfurt, Germany

Materials Science and Engineering

3

rd

International Conference on

Mater Sci Nanotechnol, Volume 3

N

ature has created many natural protein polymeric

materials suitable for use as fibers – like spider silk. Bolt

Threadshasdevelopedamolecularbiologyplatformtomimic

and/or tune the properties and inherent environmental

compatibility of these materials and manufacture them via

large-scale fermentation. Our platform includes genetic-

level control over the amino acid sequence, allowing us to

fine tune the polymer processing windows and functional

material properties. Today, Bolt Threads is capable of

producing a recombinant spider silk protein at commercial

scale and spin this material into filament and staple yarns.

Bolt Threads filaments exhibit spider silk biomimicry and can

be generated with high consistency and at large volumes.

This first fiber demonstrates the baselined capability of Bolt

Thread’s designer protein polymer pipeline. The mission of

Process Development is to continue to optimize and deploy

scalable, economically viable processes for the production of

the natively-inspired bio-derived materials with sustainability,

performance, and market advantages. This session will

describe our approach used to accelerate the launch of our

first commercial products: 1. A recombinant spider silk protein

which we spin into filament and staple yarns, and 2. Mylo

TM

a

mycelium leather. A little more about

Bolt Threads:

Bolt Threads is a vertically integrated company

driven by 100+ dynamic scientists, engineers, artists, and

operations specialists. At Bolt, our endeavors includemolecular

biology and materials science R&D, polymer production,

fiber manufacturing, product development, marketing,

merchandising, and direct to consumer sales. Bolt Threads

operatesdirecttoconsumerthroughBestMadeCo.andpartners

withwell-knownbrandssuchasStellaMcCartneyandPatagonia.

Speaker Biography

Alex Patist has over 20 years of experience in directing new product,

process development, and scale-up in the food, nutraceutical, biochemical

& biofuels industries. Since 2017, he took on the role of VP of Process

Development & Manufacturing at Bolt Threads. Before Bolt, he spent

4 years at Genomatica in San Diego, a leading biotech innovator for the

chemical industry. He has been a catalyst inmainstreaming a whole process

approach to deliver economic advantaged bioprocesses. Previously, he was

at Cargill R&D in Minneapolis. During his tenure as Director of Technology

he worked withmajor partners such as Pepsico, Coke and Kraft taking ideas

from concept to realization (for example the high intensity sweetener

Truvia®). Originally from the Netherlands, he has a BS from Hogeschool

Utrecht, MS from TU Eindhoven and a Ph.D. from the University of Florida,

all in Chemical Engineering.

e:

apatist@boltthreads.com

Alex Patist

Bolt Threads, USA

Better materials for a better world: Silk without spiders and leather

without cows