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J Parasit Dis Diagn Ther 2017

Volume 2 Issue 3

Tropical Medicine 2017

Notes:

Page 15

September 7-8, 2017 | Edinburgh, Scotland

4

th

International Conference on

Tropical Medicine, Infectious Diseases & Public Health

INVESTIGATION ON THE FAMILIAL

AGGREGATIONAND SPATIALAGGREGATION

OF HUMAN LEISHMANIA INFECTION IN

TANCHANG COUNTY, GANSU PROVINCE,

CHINA

Guan Ya-yi

a

, Zhuyao-yu

a

, Wu Wei-ping

a

, Wang Li-ying

a

, Han Shuai

a

, Wang

Ying

a

and

Bai Xue-fei

a,b

a

National Institute of Parasitic Diseases, China

b

Sichuan Provicial Center for Disease Control and Prevention, China

V

isceral Leishmaniasis, also known as kala-azar, is a

vector-borne disease caused by the Leishmania species

complex. In China, there have been a continuous popularity in

hill-type kala-azar endemic areas, mainly in southern Gansu

province and northern Sichuan province. The research aimed

to investigate whether the distribution of human Leishmania

infection showed the characteristics familial aggregation and

spatial aggregation, and provides a reference for the further

control of kala-azar. The binomial distribution goodness of fit

test and SaTScan software were applied for analyzing family

GPS positioning information and laboratory test results of the

family members. It was found that the distribution of human

Leishmania infection corresponded to binomial distribution

and did not conform to the family aggregation and spatial

aggregation. In consideration of the local population and

domestic animals were universally infected and widely

distributed in different families and regions, their role as

reservoir host during the spread of kala-azar should be

emphasized. At the same time, it also implied vector control

could be the key for kala-azar prevention and control in the

hill-type endemic areas in Gansu province, China.

Biography

Guan Ya-yi obtained her doctoral degree in Chinese Center for Disease Control

and Prevention (China CDC). Her research field is molecular epidemiology,

health economics and global health. She obtained Bachelor and Master degree

at Hunan Medical College (Changsha, Hunan province, P.R.China), Tongji

Medical College (Wuhan, Hubei province, P.R.China), and Chulalongkorn

University (Bangkok, Thailand). She has been working at the National Institute

of Parasitic Diseaseas in Shanghai, China since 1989 and taken the role

as principal investigators or key members of several projects on malaria,

leishmaniasis and echinococcosis.

guan_ml@126.com

Guan Ya-yi et al., J Parasit Dis Diagn Ther 2017