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Journal of Clinical and Experimental Toxicology | Volume: 03 | ISSN: 2630-4570
alliedacademies
November 04-05, 2019 | Prague, Czech Republic
2nd World Congress on
TOXICOLOGY AND APPLIED PHARMACOLOGY
Chemical constituents of donkey dung (Anbarnasara): Questioning the recent claims
concerning Therapeutic effects
Atefeh Hajiagha Bozorgi
Alborz University of Medical Sciences, Iran
Background : Various animal excrements have been used
as a medicine for the treatment of different diseases in
the past. Today, people still use some of these excrements,
especially female donkey dung (Anbarnasara,) by smelling
the smoke of burnt dung for some ailments like sinusitis
and bronchitis. Recently, some studies have focused on
the therapeutic activities of Anbarnasara but no one has
studied the active ingredients of it.
Objective: The aim of this study was to identify the
chemical constituents and antibacterial activities of
Anbarnasara and its smoke.
Materials and Methods: Female donkey dungs were
collected from Shahreza in May 2017. The substance was
burnt and the smoke was led to a beaker of methanol by
a distillation apparatus. Then, the methanolic extract was
dried via a rotary evaporator. Antibacterial activity of the
smoke and also the total methanolic extract of Anbarnasara
were tested on Staphylococcus aureus and Escherichia coli
via well diffusion method. Chemical constituents were
analyzed through gas chromatography-mass spectrometry
(GC–MS).
Results : The results showed that Anbarnasara and its
smoke have a very weak antibacterial activity. Regarding
chemical constituents, both total methanolic extract and
smoke extract predominantly contained toluene, xylene,
and dibutyl phthalate.
Conclusion: Previous studies showed xylene as one of the
major components of the smoke of Anbarnasara. These
articles also reported the presence of some plant-based
compounds such as glyoxal, syringol, and limonene in the
smoke. The presence of these compounds is probably due
to the donkeys’ diet. In our study, the presence of dibutyl
phthalate, an industrial plasticizer, among the components
is probably due to environmental factors. These evidences
suggested that Anbarnasara is under the influence of
environmental factors like vegetation and pollutions and
therefore, should be used as a medicine with caution.
Recent claims regarding the antibacterial, cytotoxic,
and wound healing activities of Anbarnasara should be
considered independent of these environmental factors.
Biography
Atefeh Hajiagha Bozorgi has completed PharmD from Tabriz university
and her PhD from Shahid Beheshti university, Tehran, Iran. She is an
assistant professor in Alborz university now and teaches medicinal
chemistry courses for pharmacy students. She also manages hospital
and educational pharmacies.
e:
Atefeh Hajiagha Bozorgi, J Clin Exp Tox, Volume: 03
DOI: 10.35841/2630-4570-C2-008