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June 06-07, 2019 | London, UK
2nd International Conference on
Tissue Science and Molecular Biology,
Stem Cells & Separation Techniques
Joint Event
Biomedical Research (An International Journal of Medical Sciences) | ISSN: 0976-1683 Volume 30
Clinical Separation Techniques, Drugs and Nanotechnology
Jayita Goswami
Independent Researcher and Writer, USA
Moleculesinnaturestayincomplexform.Toanalyzethose
molecules various separation techniques have evolved.
The separation can be based on size, affinity or towards a
particular bonding. This is the era of nanotechnology and
nanomedicine. Along with former cell-based treatment,
now various nanoparticle helps to activate specific drugs.
Various separation techniques will be discussed in this talk.
MALDI-TOF-ESI helps to separate and analyze bacterial and
viral proteins. We use ESI to add extra ions in the reaction
chamber. During drug production, molecules can be in isomer
and enantiomer form. To make it more effective, the same
structure gets separated during drug production.
Clinical laboratories use a lot of liquid chromatography.
HPLC-MS, UPLC is very frequently used. Nanoparticles and
Nanomedicine are taking the market. Efficiency, effectivity
and the cost cutting are important in the clinical world
and in various separation techniques. Some chemicals are
toxic for environmental disposal. Combination of liquid
chromatographyandmassspectrometrybroughtthedifferent
level of dimension in molecular separation techniques. Liquid
chromatography combined with Mass Spectrometry and the
microfluidic device gives the ultimate sensitivity to detect
single nucleotide polymorphism and an early stage of disease
detection. Drug delivery purposes various new molecules
are getting explored. Nested molecules help with the slow
release of drugs and a keeps a long-term dosage activity.
Speaker Biography
Jayita Goswami is a researcher and faculty for several years. She taught
in the colleges and performed research in various laboratories. She got
a fellowship from NIH (USA) right after her graduation. Her graduate
research was based on bioenergetics and molecular biochemistry. The
model organism was Chlamydomonas reinhardtii. This organism is getting
explored for biofuel research purposes by various research institutions.
Molecular, biochemical and biophysical techniques were used to address
my research questions. I explored the importance of the hydrogen bond
betweenmolecules. She was involvedwith cancer drug discovery research.
She worked with various breast, prostate and blood cancer cell lines and
designed drugs. She got the opportunity to explore molecular forensic
world too. She gained the expertise to make various molecular tags that
has many fold applications. One of her works got patented. She worked
in the food microbiology and infectious disease field as well. Although
she started my career with botany, my passion for the biomedical science
brought me here.
e:
Jayita Goswami, Biomed Res, Volume 30
ISSN: 0976-1683