![Show Menu](styles/mobile-menu.png)
![Page Background](./../common/page-substrates/page0006.png)
Biomedical Research
|
Volume 29
Page 44
allied
academies
CARDIOLOGY AND CARDIOVASCULAR MEDICINE
STEM CELLS AND REGENERATIVE MEDICINE
&
International Conference on
International Conference on
J u n e 1 8 - 1 9 , 2 0 1 8 | O s a k a , J a p a n
Joint Event on
BRIHH IN PATIENTS WITH DM REPERCUSSION AND DIAGNOSIS
IN STUDIES OF MYOCARDIAL PERFUSION WITH SESTAMIBI
Gómez Garibo José Rubén
Naval General Hospital of High Specialty, Mexico
I
t is known that the LBBH has different etiologies, among which, wemust consider the obstructive coronary atherosclerosis,
mainly in the anterior descending coronary artery, however, there have been no analyzes that specifically assess the
presence of LBBH in diabetic patients and its Impact on myocardial perfusion studies with sestamibi. The purpose of this
study is to know if the diabetic patient, with LBBB, will increase the probability that said blockade is related to obstructive
coronary atherosclerosis, detected by myocardial perfusion studies, with sestamibi as a radiopharmaceutical. Additionally,
the diagnostic accuracy of the study will be assessed to adequately characterize the absence or presence of CAD. In a
retrospective way, 128 patients with LBBH were selected, sent to the nuclear medicine service from 2013 to 2016, with
suspicion of CAD. Of these patients, 68 (41 women and 27 men, average age 65 years, age range of 54 to 88 years) had
diabetes mellitus, among other known risk factors. The remaining 60 patients (36 women and 24 men, average age 69
years, age range of 54 to 88 years), suffered from other risk factors other than diabetes. The patients followed the protocol
for the preparation and conduct of myocardial perfusion studies of the American guidelines. Patients without BRDHH were
excluded. Stress tests of all patients were performed with dipyridamole. The reference test against which the results were
compared, was therapeutic coronary angiography, in the patients who were found to have CAD by our method. And when
the treating physician considered it, in patients without CAD by our method, coronary angiotomography was
requested.Ofthe 68 patients with diabetes mellitus, 52 were found to have CAD and 16 without CAD. Of the 60 non-diabetic patients,
48 were found to have CAD and 12 without CAD. The chi square test was used to establish a relationship between the
known variables (diabetes and branch block / non-diabetics and branch blockade, healthy and sick). The null influence of
diabetes mellitus on the increase in CAD in patients with LBBH, was considered as a null hypothesis. The result was that
such hypothesis was confirmed. Regarding the diagnostic accuracy of the nuclear medicine study in patients with diabetes,
it was 94.1%, sensitivity of 94.2% and specificity of 93.8%. In non-diabetic patients, the diagnostic accuracy of the nuclear
medicine study was 93.8%, sensitivity of 93.8% and specificity of 93.8%. In both cases, positive predictive values were
found, above 97%.
j_r
_ggotmail.comBiomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C2-006