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Pharma Summit 2018 & Gastro Summit 2018 Asian Journal of Biomedical and Pharmaceutical Sciences | ISSN: 2249-622X | Volume 8
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Shrikant Kadam et al., Asian J Biomed Pharmaceut Sci 2018, Volume 8 | DOI: 10.4066/2249-622X-C5-014
ISOLATION AND CHARACTERISATION OF
BIOACTIVE COMPOUNDS OF MEDICINAL
PLANTS REPORTED TO HAVING
ADAPTOGENIC PROPERTIES
Shrikant Kadam
1
, Pawar Vinod S
1
, Vikrant Taware
1
and
Shivakumar Hugar
2
1
SVPM’S College of Pharmacy, India
2
BLDEA’s SSM College of Pharmacy and Research Centre, India
P
lants biosynthesize numerous secondary metabolites possessing diverse
chemical structures. Search of bioactive compound responsible to elicit
adaptogenic effect has been herculean task.
In the present study also, we have isolated the quercetin and gallic acid from
methanolic extract of
G. lucidum
and gallic acid from methanolic extract of
P.
Senega
. The preliminary TLC studies of MEGL and MEPS demonstrated pres-
ence of phenolic compounds. Therefore, for isolation of these phenolic com-
pounds, methanol extract was fractionated by using Toluene: ethyl Acetate:
Formic acid (v/v/v) (7:5:1) and characterized by spectral (UV, IR, 1HNMR and
Mass) analysis.
Fractions were separated by using column chromatographic separation The
obtained spectral data was compared with literature and showed the com-
plete agreement of quercetine and gallic acid. The presence of these bioac-
tive components could be responsible for the observed potential adaptogenic
activity.
Shrikant Kadam working as a Assistant Professor in the
Department of Pharmaceutical Chemistry, SVPM’s Col-
lege of Pharmacy, Malegaon (Bk), Baramati, affiliated
to Savitribai Phule Pune university, Pune, India. He has
received M.Pharm degree from Shivaji University Kol-
hapur. He is having 11 years of teaching experience in
Biochemistry and Pharmaceutical Analysis. His area of
research lies in the field of Pharmaceutics, Biotechnolo-
gy and Analysis. He is a life member of Association of
Pharmaceutical Teachers of India (APTI) and Registered
Pharmacist of Maharashtra State Pharmacy council
(MSPC), India.
shrikant.kadamsvpm@gmail.comBIOGRAPHY