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Journal of Pathology and Disease Biology | Volume 2

September 06-07, 2018 | Edinburgh, Scotland

Pathology and Surgical Pathology

International Conference on

Case report: Telangietactic osteosarcoma in a 20 year old male

Ayman Ismail

Mohammed VI University Hospital, Morocco

elangiectatic osteosarcoma (TO) is one of the rare

subtypes of osteosarcoma (OS) and accounts for less

than 4% of all tumors in the appendicular

is a

rare variant of OS with distinctive radiographic, gross, and

microscopic features and prognostic implications. Although

conventional OSs may contain telangiectatic elements,

only those composed almost entirely of telangiectatic

tissue are generally considered true examples of this entity.

We present the case of a 20-year-old male patient who

consulted for wrist pain. An X-ray showed a lytic destructive

lesion of the distal left radius while magnetic resonance

imaging revealed features highly suggestive of telangiectatic

osteosarcoma. The lesion was biopsied which confirmed

osteosarcoma, with difficulty subtyping due to the limited

material available. After four cycles of chemotherapy the

patient underwent an elbow disarticulation. The specimen

was sent to pathology where gross examination showed

cystic lesion filled with blood of the of the distal radial

metaphysis. Histological examination showed that the

lesion is composed largely of hemorrhage and necrotic

debris. Blood pools do not demonstrate an endothelial

lining. Within these blood lakes, variously sized septa are

identified, which contain atypical stromal cells with nuclear

hyperchromasia, atypical mitoses, and pleomorphism.

Telangiectatic osteosarcoma is a rare variant, representing

around 3% of osteosarcomas overall. The main differential

radiographically, grossly and on histology is with aneurysmal

bonecystandboththeselesionstendtooccurinthemetaphysis

of long bones with a peak incidence in the 2nd decade.