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academies
17
th
International Conference on
4
th
International Conference on
NEUROLOGY AND NEUROSCIENCE
&
MENTAL HEALTH AND PRIMARY CARE
October 16-18, 2017 | Toronto, Canada
J Neurol Neurorehabil Res 2017 | Volume 2 Issue 3
Background:
Of all the side effects of chemotherapy, CINV
remains one of the most dreaded by patients. Evidence
based guidelines recommend nabilone for prevention
of anticipatory chemotherapy-induced nausea/vomiting
(ACINV) but not for rescue nausea/vomiting (RNV). Nabilone
may increase the risk for over sedation and falls. The
purpose of the study was to characterize the frequency
and patterns of Nabilone prescribing and administration as
well as to compare the rate of falls in patients prescribed
vs non-prescribed nabilone for nausea/ vomiting among
hospitalized oncology patients.
Methods:
A retrospective study was conducted by reviewing
the medical charts of 300 oncology patients admitted in
months of June-August 2016 in tertiary care hospitals in
KPK. Prescribed indications and actual administration of
Nabilone as well as documented patient falls were recorded.
Potentially inappropriate prescriptions were defined as
frequency <8 hours, dose >2mg, multiple concurrent as
needed prescriptions. Inappropriate administrations were
not given in the prescribed 1st/2nd/3rd line sequence.
Nabilone prescriptions for neuropathic analgesia were
excluded.
Result:
Out of 300 patients, 61% (n=183) patients with mean
age 51±19 years were prescribed nabilone. The length of
stay was 14±11 (p-value=0.0001). The results showed that
Nabilone was prescribed for RNV was 49% (n=91) while
for ACINV, it was only 21% (n=38). Inappropriate dosing
frequency was 9%, concurrent prescriptions were 17% and
inappropriate administration was 19% (n=53) patients.
Interestingly fall rate in nabilone prescribed patient’s p value
was 0.7 and among non-prescribed patient’s p value was 1.5.
Conclusion:
Potentially inappropriate prescribing and
administrations of Nabilone for rescue nausea/vomiting
were common. Estimated fall rate was not significantly
different between patients prescribed and not prescribed
Nabilone in this small pilot study. Informed consent was
obtained from all patients..
Speaker Biography
Sardar Alam, Pharm.D, now a pre-doctoral student in the school of medicine, University
of Crete, Greece. He is a registered pharmacist. His research interest includes oncology,
CAM therapies and drug delivery systems. His research articles and reviews have
been published in international peer-reviewed journals as well as in conferences.
His research expertise includes prescriptions interventions, dose adjustment. He
has experience in hospital as well as pharmaceutical industry where he works as a
pharmacist as well as R & D officer respectively.
e:
sardaralam754@gmail.comThe frequency and patterns of Nabilone prescribing and administration among hospitalized
oncology patients
Sardar Alam
1
, Muhammad Safdar
1
, Muhammad Tariq
2
, Abdul Zahir
3
and
Waqar Alam
4
1
Gomal University DIK, Pakistan
2
Hayatabad medical complex hospital, Pakistan
3
Hubei medical University, Hubei province China
4
Dinajpur Medical College,Bangladesh