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Allied J Med Res 2017
Volume 1 Issue 2
Herbal Medicine 2017
September 01-02, 2017 London, UK
3
rd
International Conference and Expo on
Herbal & Alternative Medicine
Page 61
Efficacy and safety of Hepano tablet in
liver disorder patients with abnormal liver
function test: a randomized active controlled
prospective clinical study
Satyendra Kumar
Jamia Hamdard University, India
H
epano tablet is anAyurvedic herbal formulation studied
in pre-clinical models for safety and hepatoprotective
efficacy. The current study was a randomized, active
controlled, multicentre, prospective clinical study that
aimed to evaluate hepatoprotective efficacy and safety of
Hepano tablets. Male and female liver diseases patients
(18-65 years) with abnormal liver function tests were
randomized to receive two tablets twice daily orally of
either Hepano or a marketed comparator for 8 weeks
with follow up at day 7, 14, 28 and 56 during treatment
period and thereafter at day 84. Results were assessed
from baseline to end of treatment basis changes in liver
function tests and improvement in clinical symptoms of
icterus in both the groups. Safety was assessed at all the
visits basis changes in laboratory parameters and adverse
event reporting for all cases who took at least one dose of
the study drug. Hepano tablet and marketed comparator
showed significant improvement in Liver functions - serum
aspartate transaminase (AST), alanine transaminase
(ALT) and total, direct and indirect bilirubin levels and
a significant reduction in clinical symptoms of icterus
that was comparable at all the visits. Results concluded
Hepano tablets can significantly improve liver function
tests and clinical symptoms in liver disease patients and
could be consumed safely.
satyendra.kumar@mail.daburAllied J Med Res 2017