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Journal of Biotechnology and Phytochemistry| Volume: 2
October 25-26, 2018 | Frankfurt, Germany
Joint Event
Biotechnology & Medical Microbiology
World Congress on
3
rd
International Conference on
Food Science & Technology
Prevalence of upper respiratory tract fungal infections in HIV patients clinically symptomatic suspects
for pulmonary
Mycobacterium tuberculosis
attending Kiwoko Hospital - Nakaseke District (Uganda)
Yusuf Muyingo, Bakyayita Charles Bwanika
and
Emunyu Jude
Kiwoko Hospital, Uganda
Introduction:
Fungal upper respiratory tract infections are a
major cause of morbidity and mortality among HIV positive
patients. However, due to similar clinical symptoms with
Mycobacterium tuberculosis
it has been a challenge to correctly
diagnose upper respiratory tract fungal infections (URFIs) in HIV
patients.
Objectives of the study:
The study sought to determine the
prevalence of the URFIs in HIV positive patients clinically
symptomatic for pulmonary TB attending Kiwoko hospital with
reference to sex, age group, and to understand its association
with HIV co-infection.
Methodology:
A cross sectional study on 138 subjects selected
by simple random sampling was conducted. Their sputum
samples quality was assessment for both macroscopic (Medical
Research Council method) and microscopic (Bartlett scoring
method) examinations followed by immediate Direct KOH
smears, Gram’s staining technique for the presence of hyphae
and yeasts. Culturing was done on 5% Sheep Blood agar and
Sabouraud’s dextrose agar for screening characteristic colonies
of fungal organisms including their texture.
Mycobacterium
tuberculosis
results were directly obtained from gene expert
data system.
Results:
30.4%of the participantswere screenedURFIs positive,
10.1% with
Mycobacterium tuberculosis
, 3.6% screened
positive for both TB and URFIs and 6.5% with
Mycobacterium
tuberculosis
only. 17.4 % females and 13.0 % males were
screened positive for upper respiratory fungal infections, while
32.6% females and 37.0% males were screened as negatives.
2.2%, 3.6%, 13.8%, and 10.1%of the participants were screened
positive for URFIs according to age groups 0-14, 15-24, 25-49,
and ≥50 years respectively.
Conclusions:
URFIs are clinicallymisdiagnosed as TB inHIVpatients
symptomatic for pulmonary
Mycobacteriumtuberculosis
.
Recommendation:
Fungal screening is co-currently performed
with TB testing amongHIVpatients presentingwith TB symptoms
and ensuring that the community is sensitized on this.
Speaker Biography
Yusuf Muyingo has completed his diploma at the age of 29 years from Mildmay
Institute of Health Sciences, Uganda. He is the director of Health Competence
Implementers Uganda, Uganda. He looks forward publishing guide lecture notes in
medical laboratory technology and practical guides and practical training sessions
in the same field in Uganda to promote competence. Has been serving as a medical
laboratory personnel of Kiwoko hospital since 06/ 2012. He has been contributing his
effort in medical camps and awareness campaigns in Uganda.
e:
yusufmuyingo564@gmail.com