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Res Rep Gynaecol Obstet 2017 | Volume 1 Issue 4
November 02-03, 2017 | Chicago, USA
Embryology and In vitro Fertilization
World Congress on
The effects of advancing age on semen quality and sperm DNA fragmentation index
Carlos Rivas, Láyonal Acosta, Jheny Díaz, Lissett Chiscul, Elmer Chavez
and
Luis Gonzales
Gestar
In Vitro
, Perú
Background:
The aim of the present study was to determinate
the correlation between the advancing age on semen quality
and sperm DNA fragmentation index.
Methods:
Prospective study conducted at the Laboratory of
Andrology ¨Gestar
In Vitro
¨ (Chiclayo – Perú). 693 patients were
analyzed from September 2013 to September 2017. The semen
samples were analyzed acording to the criteria WHO 2010.
The Index Sperm DNA fragmentation (IFA) was determined
using the tets Sperm chromatin Dispersion. For determination
on the median was used SPSS 22 software. In the population
was determined the Spearman correlation between sperm
parameters and IFA and age.
Results:
Thepatients’ ages ranged17 to70years. Themeansand
medianwere 37.73 and 37 years respectively. The patientswere
divided into four groups: <30 years, 30-39 years, 40-50 years
and ≥50 years. We determined an inverse correlation between
the age and volume (r=-0.134
P
=0.000), progressive motility
(r=-0.136
P
=0.000), normal morphology (r=-0.101
P
=0.008),
vitality (r=-0.167
P
=0.000). We determined a significant positive
correlation between age and IFA (r=0.302
P
=0.000). Patients ≥
45 years showed higher levels of IFA (23.5% vs 16%
P
=0.000)
compared with patients <45.
Conclusions:
The results indicate that advanced age effects
semen quality and increases the IFA.
Speaker Biography
Dr Carlos Rivas is a physician in reproductive medicine. He is the medical director of
Gestar
In Vitro
center, he is the member for Latin American Net of Human Reproduction
and society of Gynecology and Obstetrics in Peru. He is also attached with membership
of association and society of reproductive medicine.
e:
carlosantoniorivast@gmail.com