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Page 63
allied
academies
Nov 22-23, 2018 | Paris, France
Joint Event
Nutrition and Health
16
th
International Conference on
26
th
International Conference on
Diabetes and Endocrinology
&
Journal of Insights in Nutrition and Metabolism | Volume 2
Notes:
Maternal adiponectin concentration and food intake in gestational diabetic women: A case control study
Zamzam Paknahad
Isfahan University of Medical Sciences, Iran
Background:
Gestational diabetes mellitus (GDM) is an
impaired fasting glucose condition during pregnancy.
Adiponectin is a polypeptide hormone that is extensively
released by adipocytes which regulate energy homeostasis and
carbohydrate and lipid metabolism. In addition, adiponectin
has antidiabetics and anti-inflammatory properties. The
aim of our research was to study about the relationship
of adiponectin levels to GDM and glucose intolerance.
Methods:
Weselected25GDMwomenand35healthypregnant
subjects (18–46 years) who were screened between 24 and 28
weeks of gestation based on the result of oral glucose tolerance
test (OGTT). We designed case-control study and measured the
concentration of serum adiponectin and compared between
the groups. Serum adiponectin concentration was detected
using enzyme linked immunosorbent assay (ELISA). Dietary
information was collected by Food Frequency Questionnaire.
Results:
Serum adiponectin concentration was significantly
lower in the subjects with GDM (5.10 ± 2.15 ng/mL vs. 7.86
± 3.52 ng/mL, p = 0.001) than healthy pregnant subjects. The
mean concentration of fasting blood glucose was considerably
lower in control subjects (86.9 ± 9.0 mg/dL vs. 175.9 ± 20.1 mg/
dL, p < 0.001) in comparison to GDM subjects. Dietary intake
of foods from milk, cereals and vegetables groups at GDM
mothers were significantly lower than healthy group(p<0.05).
Conclusion:
Our findings showed that serum concentration
of adiponectin was significantly lower in gestational diabetic
women and this may help to predict the risk of GDM.
e:
paknahad@hlth.mui.ac.ir