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allied
academies
Nov 22-23, 2018 | Paris, France
Joint Event
Nutrition and Health
16
th
International Conference on
26
th
International Conference on
Diabetes and Endocrinology
&
Journal of Insights in Nutrition and Metabolism | Volume 2
The investigation of changes some blood profiles with oral green tea extract intake in type 2 diabetic
rats
Maryam Azhdari
Ahvaz Jundishapur University of Medical Sciences, Iran
Background:
Diabetic mellitus (DM) is a chronic disease
characterized by high glucose levels, lipoprotein abnormalities
and altered intermediarymetabolismof major food substrates.
In this study, we have investigated effects of green tea extract
(GTE) on some blood profiles like: Serum glucose, hemoglobin
A1C (HbA1C), triglyceride (TG), low density cholesterol (LDL-C),
high density cholesterol (HDL-C) and total cholesterol (TC) in
type 2 diabetic rats.
Methods:
Type 2 diabetes was induced by 10% fructose
administration to male Wistar rats (120-140g) for 8 weeks.
Forth animals divided into two groups (n=20): diabetic group
without green tea extract (GTE) and diabetic group with
100mg/kg body weight GTE for eight weeks. Some blood
profiles like: Serum glucose, HbA1C, TG, LDL-C, HDL-C and
TC were measured before the experiment and by the end of
period (8 weeks) in all groups.
Results:
This study showed significant beneficial effects of
green tea extract in decrease the levels of TG, LDL-C and TC and
increase HDL-C in comparedwith those of diabetic rats without
GTE, but we did not find significant changes in Serum glucose,
hemoglobin A1C between two groups.
Conclusion:
The results of this study showed beneficial effects
of green tea extract on lipid profiles of diabetes rats.
e:
azhdari_mar@yahoo.com