22 / 26
allied
academies
Journal of Biotechnology and Phytochemistry
Volume 1 Issue 3
Chemistry World 2017
Page 74
November 13-15, 2017 Athens, Greece
7
th
World Congress on
Chemistry
Heating with inorganic nanoparticles:
applications in life science
Pablo del Pino
USC Center for Research on Biological Chemistry and Molecular Materials,
Spain
The capability of being able to release heat upon remote
electromagnetic (EM) exposure has opened newopportunities
for a variety of goals in life sciences. Local heating with
colloidal nanoparticles (NPs) has been used for killing tumoral
cells, drug-release applications, ultralow detection of tumoral
markers, imaging
in vivo
and
in vitro
, or even sterilization.
In the frame of oncological hyperthermia, both magnetic and
plasmonic NPs have been investigated as nanoheaters and can
be remotely activated by radiation that do not or minimally
interact with physiological tissues and fluids. Actually, the
major challenge concerning colloidal chemistry within this
framework resides in being able to produce NPs that absorb
in EM regions where tissue absorption remains minimum,
i.e., biological windows. Engineered nanomaterials with
tailored heating performance, as well as suitable organic
coatings, are continuously developed toward more efficient
interactions with EM radiation and the performance of more
complex tasks in biological environments. Moreover, these
materials can be used simultaneously as contrast agents by
using imaging techniques that rely on their magnetic (e.g.,
MRI) or plasmonic behavior (e.g., OI), thereby enabling
theranostic NPs. In this talk, several examples of nanoheaters
for applications in life science will be discussed.
pablo.delpino@usc.esJ Biotech and Phyto 2017