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Asian Journal of Biomedical and Pharmaceutical Sciences | ISSN: 2249-622X | Volume 8
&
Joint Event
Chemistry and Organic Chemistry
Biomedicine & Pharmacotherapy
International Conference on
8
th
World Congress on
October 22-23, 2018 | Frankfurt, Germany
Risk assessment by chronic toxicity to exposure of magnesium at a renal level in rats of the species
Rattus Norvegicus
Giancarlo Mendez Agreda
Universidad Nacional Mayor de San Marcos, Peru
A
histological examination from kidneys, specifically at the
level of renal cortex and medullary thick ascending limb
of Henle’s loop, in a group of albino rats of the species Rattus
norvegicus Holtzman strain, to which were administered
orally magnesium chloride Ad. Libitum at concentrations
below the LD50 but above the RDA, showed sublethal
damage evidenced by a slight swelling that encompassed
the medullary and cortical area in the study group compared
with the control group. In addition to this, biochemical
parameters in blood and urine were also affected, which
has demonstrated that the consumption above the RDA and
without the guidance of a health professional is detrimental
to long-term health.
Speaker Biography
Giancarlo Mendez Agreda has completed his MSc at the age of 30 years old at University
of Turku, Finland. He is a pharmacist graduated fromUniversidad Nacional Mayor de San
Marcos(Peru).Healsocountswithexperienceatpharmaceuticalindustryasaformulator.
e:
gianmenag@gmail.comGiancarlo Mendez Agreda, Chemistry and Biomedicine 2018, Volume 8
DOI: 10.4066/2249-622X-C4-012