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academies
Cell Science, Stem Cell Research &
Pharmacological Regenerative Medicine
November 29-30, 2017 | Atlanta, USA
Annual Congress on
Adv cel sci tissue cul 2017 | Volume 1 Issue 2
A study on effect of anti-tuberculosis drugs on liver function
Liliane Uwimana
University of Rwanda, Rwanda
A
study is aimed to assess the effect of anti-tuberculosis
drugs on liver function among the patients who
attended King Faisal Hospital during the period of two years.
A sample of 165 tuberculosis patients receiving the standard
treatment of TB drug during the period of two years was
done, only 22 patients for whom liver function test was
done before and during treatment with anti-tuberculosis
(TB) drugs were considered. The hepatotoxicity consisted
of high concentration of ALT (Alanine Amino Transferase)/
AST (Aspartate Amino Transferase), Jaundice or high
concentration of total bilirubin. The result revealed that
among 22 patients, 68.5% had ALT/AST at normal range at the
beginning of treatment with anti TB drugs. After 3 months of
anti TB therapy the record showed that 45% of them has ALT
beyond the normal range and after 6 months of therapy the
ALT level showed high frequency of liver dysfunction up to
79%. It is essential to monitor liver function from beginning
of therapy with anti-tuberculosis drugs.
Speaker Biography
Liliane Uwimana is working as a Pharmacist in Pharmacie Royale and has completed
her Bachelor’s degree from University of Rwanda. She has worked in King Faisal
Hospital as Pharmacist where she did her research on Effect of Anti Tuberculosis Drugs
on Liver Function.
e:
lilianeuwimana58@gmail.com