cardiology-nutrition-health-2018-posters-abstracts

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academies

Journal of Nutrition and Human Health | Volume 2

October 29-30, 2018 | London, UK

Joint Event

Nutrition and Fitness

International Conference on

World Congress on

Card i o l ogy

Validity of Renal Denervation for the treatment of resistant hypertension. Experience in Honduras

Hugo Chinchilla

Universidad Complutense de Madrid, Spain

pproximately 25% of the adult population of the

industrialized countries suffers from arterial hypertension.

Within this population there is a subgroup that despite an

optimal treatment that includes 3 or more classes of drugs at

maximum dose persists with high blood pressure figures both

in the office and in the 24-hour monitoring. (AMBP). This is a

population that represents 4-5% and has a very high risk of

complications and cardiovascular, renal and cerebrovascular

comorbidities with high mortality. Hence the importance

of its detection and control in specialized units of HTA.

From the physiopathological point of view there are subtypes

of resistant hypertension where sympathetic hyperactivity

plays a central role. Hence the advent of non-pharmacological

co-adjuvant therapies that aim to decrease renal sympathetic

activity. Themost studied andmost experienced clinical method

isKidneySympatheticDenervationwithradiofrequencycatheter.

There are several designs on the market. Despite the good

results in the first studies: SYMPLICITY-HTN I and SYMPLICITY-

HTN II. There was a slowdown in the use of this treatment as

a result of the disappointing results of SYMPLICITY-HTN III.

In this review we make a critical analysis of the SYMPLICITY-

HTN III study and review the latest evidence demonstrating the

current validity of the method in this specific subgroup of true

hypertensive resistant patients, the importance of adequate

selection and operator experience. We also show the results

of the local experience where we observed a high percentage

of responders in relation to the technique used, since from

the first cases we used an off-label technique where a greater

number of applications are made on average 8 per artery and

in Secondary branches smaller than 4 mm. In perspective we

analyze the results with multipolar devices of more recent

design, their advantages and impact on the results.

Notes: