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allied
academies
Joint Event
February 21-22, 2019 | Paris, France
Microbiology & Applied
Microbiology
2
nd
International Conference on
World Congress on
Wound Care, Tissue Repair
and Regenerative Medicine
&
Journal of Trauma and Critical Care | Volume 3
Slight improvement of the effectiveness in treating cleft lip scars with silicone gel versus silicone
sheet: A secondary analysis
Qiaowan Lee
1
and Yensheng Wang
2, 3
1
Taipei City Hospital, Taiwan
2
Yale University School of Public Health, USA
3
Chang-gung Memorial Hospital, Taiwan
Introduction:
Silicone sheet is often used for preventing cleft
lip scar postoperatively with concerns of ingestion, application
site irritation and short application time. Silicone gel has day-
long application duration with better safety. Previous study
suggested no difference between forms of silicone in treating
cleft lip scarring without controlling potential confounders. We
aimed to evaluate the effectiveness of silicone gel versus sheet
in a different model, controlling surgical gap, side and patient
effects.
Method:
Datawas retrieved fromprevious studywith additonal
information from the author. In short, silicone gel/sheets were
randomlyassigned to thepatients. Clinical scar evaluationscores
(VSS, VAS, width) were measured 6 month after application.
Transformation was performed for normailzation and direction
purpose. Generalized linear model was performed controlling
the measurement, age, gap and patient effects with Tukey’s
adjustment. Sensitivity analysis was performed to compare the
result.
Result:
There are 29 observations in sheet groupwithmean VSS
0.46 (SD 0.11), mean 10/VAS 1.42 (SD 1.20) and mean width
2.75 (SD 1.44). There are 26 observations in gel group, with
mean VSS 0.41 (SD0.13), mean 10/VAS 1.35 (SD0.18) andmean
width 2.06 (SD 1.71). Silicone gel had a lower score compared
to sheet after tukey’s adjustment. (p=0.0048, 95CI: 0.05, 0.26).
Sensitivity analysis showed a similar result.
Conclusion:
Silicone gel appeared to slightly improve post-
operative cleft lip scars compared to silicon sheet. With the
advantage of safety and patient-friendly features, silicon gel
could be recommended for postoperative care of cleft lip scars
in infants.
Speaker Biography
Qiaowan Lee has completed her MD at Chang-gung Memorial Hospital, Taiwan in
2015. She devoted to clinical studies that discover potential treatments for surgical
wounds. Qiaowan is currently a resident doctor at Taipei City Hospital, Taiwan.
e:
DAZ06@tpech.gov.twQiaowan Lee et al.
, J Trauma Crit Care, Volume 3
DOI: 10.4066/2591-7358-C1-003