4 / 12
Page 50
allied
academies
J u l y 2 3 - 2 4 , 2 0 1 8 | R o m e , I t a l y
Note:
TRADITIONAL
MEDICINE AND ACUPUNCTURE
8
th
International Conference on
Journal of General Internal Medicine
|
ISSN: 2591-7951
|
Volume 2
Traditional 2018
ETHNOBOTANICAL SURVEY OF MEDICINAL
PLANTS USED IN PHARMACOPEIA TO
TREAT DIABETES IN GABON AND
IN VIVO
ACTIVITIES OF FIVE OF THEM
Pauline Tjeck, Denis Zofou, Jules Clément
and
Alain Souza
Sciences Technical University of Masuku, Africa
Background:
Diabetes mellitus is a disease highly associated with lifestyle.
In Sub-Saharan Africa, Gabon is the fourth most affected country. As in
most developing regions, people commonly use medicinal plants for various
diseases including diabetes. The purpose of the present work was to identify
the plants used in the Gabonese pharmacopoeia to treat diabetes, and to
evaluate the activity of five of them still unexplored.
Methods:
An ethnobotanical survey was conducted in three provinces of
the country, to identify medicinal recipes used by traditional healers to treat
diabetes. The antidiabetic potential of five selected species was evaluated
using both the Oral Glucose Tolerance Test (OGTT). Acute toxicity tests were
also performed, using albino mice.
Results:
Ethnobotanical data revealed that 50 plants commonly used to treat
the disease locally in three of the provinces surveyed. Nine of these plants
were more cited as a cure for diabetes, with citation rates ranging from 6 to
10%. OGTT results showed that animals pre-treated with extracts had a faster
blood glucose recovery than the control group.
Guibourtia tessmanii
and
Milicia excelsa
extracts demonstrated better hypoglycaemic activity (61.67%
and 53.06%, respectively). None of the extracts showed significant toxicity.
Conclusions:
Additional studies are underway to confirm the efficacy and
safety of these plants.
Pauline Tjeck et al., Arch Gen Intern Med 2018, Volume 2 | DOI: 10.4066/2591-7951-C1-003
Pauline Tjeck is a PhD student of Animal Physiology
and Pharmacology at the Faculty of Sciences, Sci-
ences Technical University of Masuku, Gabon. She is
currently completing a research project in antidiabetic
medicinal plants at University of Buea, Cameroon, as
an OWSD funded-exchange student. In 2015, she was
winner of Gabon-Oregon Seed Grant on antidiabetic
medicinal plants. In 2013, at the University of Reunion,
France, she has completed a master’s degree in Ecol-
ogy where she gained much experience in the impor-
tance of plants as medicines.
tjeckpauline@gmail.comBIOGRAPHY