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Journal of Clinical and Experimental Toxicology | Volume: 03 | ISSN: 2630-4570

allied

academies

November 04-05, 2019 | Prague, Czech Republic

2

nd

World Congress on

TOXICOLOGY AND APPLIED PHARMACOLOGY

Partial characterization, efficacy tests, clinical and histological evaluation of a plant

species (Montanoa) in the process of healing superficial wounds in Murine model

Galaviz Hernández Stephania

Instituto Politécnico Nacional, México

H

ealing and regeneration processes take place in all

parts of the human body, while regeneration describe

the specific substitution of the tissue, i.e. the superficial

epidermis, mucosa, skin repair displays an unspecific form

of healing in which the wound heals by fibrosis and scar

formation. Rats and mice represent an ideal preclinical

model to study new products. However, wound healing in a

mouse is fundamentally different to that of humans where

the repair process is then dependent on epithelialization,

cellular proliferation and angiogenesis, which closely

mirror the biological processes of human wound healing,

allows for testing of promising agents that may promote

rapid healing like Montanoa Grandiflora, which have been

considered as promising systems of phytopharmaceutical

administration by the pharmaceutical industry, mainly

because they are biocompatible, available in nature, non-

toxic and economical in its elaboration in order to satisfy

the demand presented today. Healing of skin wounds is a

highly complex process aimed at recovering the integrity

of the tissue, allowing its regeneration and restoring its

functions.

Biography

Galaviz Hernández Stephania is a Biotechnology Engineer and currently

studying the master’s in advanced technology at the Instituto Politécnico

Nacional. He has done bioinformatics studies developing three -

dimensional models of the variation in the allele – specific expression

in the developing mammalian heart and he is also currently involved in

the investigation of phytopharmaceutical to assess its healing power in

superficial, deep wounds and diabetic foot ulcers.

e:

stephgalavizher@gmail.com

Galaviz Hernández Stephania, J Clin Exp Tox, Volume: 03

DOI: 10.35841/2630-4570-C2-009