toxicology-2019-posters-abstracts

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Journal of Clinical and Experimental Toxicology | Volume: 03 | ISSN: 2630-4570

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November 04-05, 2019 | Prague, Czech Republic

World Congress on

TOXICOLOGY AND APPLIED PHARMACOLOGY

Scorpion toxins as drug and pharmacological tolls candidates

Elisabeth Ferroni Schwartz

University of Brasilia, Brazil

corpions are known for their dangerous stings that can

result in severe consequences for humans, including

death. Neurotoxins present in their venoms are responsible

for their toxicity, and due to their medical relevance, toxins

have been themainmotive for scorpion toxins research field.

On the other hand, for thousands of years, scorpion venoms

have been applied in traditional medicine, mainly in Asia

and Africa. With the advent of novel methodologies for the

massive study and characterization of venom components,

several drug candidates have been found with the potential

to tackle many of the emerging global medical threats.

Scorpions have become a valuable source of biologically

active molecules, from novel antibiotics to potential

anticancer therapeutics. Due to their pharmacological

action on ion channels and their clinical relevance,

neurotoxins have drawn attention as useful scaffolds for the

development of drugs, and new pharmacological tolls. Most

of the knowledge about the structure and functioning of ion

channels was obtained using animal toxins that modulate

these membrane proteins, especially scorpion toxins. This

talk will summarize the scorpion toxins that are the most

promising candidates for drugs and pharmacological tolls.

Biography

Elisabeth Ferroni Schwartz has completed her PhD from São Paulo

University, SP, Brazil. She is professor of University of Brasilia, DF, Brazil.

She has over 60 publications that have been cited over 1200 times, and

her publication H-index is 21. Her main research subjects have been

scorpion toxins, and ion channel modulators.

Elisabeth Ferroni Schwartz, J Clin Exp Tox, Volume: 03

DOI: 10.35841/2630-4570-C2-009