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Journal of Biomedical Research | ISSN: 0976-1683 | Volume 30
March 14-15, 2019 | London, UK
T issue Engineer ing, Stem Cel ls and Regenerat ive Medicine
Cel l and Gene Therapy
World Congress on
International Conference on
&
Joint Event
Biological effects of different intensities of blue-enriched white light in light emitting diode (LED) on
Caenorhabditis elegans
Aldana Aldawsari
Princess Nourah Bint Abdul Rahman University, Saudi Arabia
Caenorhabditis elegans is small free-living and bacterial-
feeder rhabditid nematode. It is a good model to study
the effects of light emitting diode (LED) on the living systems
because of its biological characteristics; such as short lifespan of
two to three weeks and easy maintenance at the temperature
of 20oC. Multiple cells of C. elegans including gut, muscle and
neuronal cells share homology with humans. Therefore, it has
offeredmany valuable insights into the field of human biological
science. This study aims to analyse whether the chronic
exposure of the nematode C. elegans to the blue-enriched
white light in LED light from egg to adult can impact the biology
and behaviour of C. elegans. In this analysis, four treatments
were prepared to evaluate these effects that were exposed to
no light (dark) which is the control, low-blue enriched, medium-
blue enriched and high blue enrichedwhite in LED light sources.
The results showed that the low- blue enriched treatment was
very much similar to control. In medium-blue and high-blue
enriched exposed treatments, the worms acted differently in
comparison of control with significant biological differences.
It was observed in the life span assay, that the mortality rate
after 48 h of exposure to low, medium and high-blue light was
significantly higher than the control. The worms that were
developedwhile exposed to LED light showed less tolerance and
higher mortality when exposed to heat (35oC) and cold (4oC).
The reproduction (brood size) was significantly low in Medium
and High-blue light comparing to control. The locomotion (body
bends) within 20 second was significantly lower in medium-
blue light with irregular pattern of movement, and the worm
keeps moving in the same area in high-blue light. Therefore, the
findings also help in understanding the impact of blue enriched
white in LED lights on living organisms and humans.
Speaker Biography
Aldana Aldawsari has completed her master’s degree at the age of 25 years from Texas
Southern University, USA. She is a researcher in biology who confirmed at which level the
blue light is disastrous for our health. She has been involved with studies related to biology.
She participated in many scientific conferences, seminars and activities in United States of
America. At present, she is a lecturer in Princess Nourah Bint Abdul Rahman University, SA.
e:
Aldana Aldawsari , Biomed Res, Volume 30
DOI: 10.4066/biomedicalresearch-C1-025