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Page 31

allied

academies

November 21-22, 2019 | Singapore

Global Experts Meeting on

12

th

International Conference on

STD-AIDS and

Infectious Diseases

Allergy, Immunology

and Rheumatology

Joint Event

&

J Infectious Disease Med Microbiol, Volume 3

The drug allergy app: Key strategy to overcome barriers to best practice

Shuayb E

3

, G Calisti

1

, A Amini

2

, L Hernandez

2

, L Owens

1

, R Carman

1

, K Dodgson

1

, K Alexander

1

and

T Garcez

1

1

University NHS Foundation Trust-MFT, UK

2

Birmingham City University, UK

3

University of Manchester, UK

Drug allergies are common. They limit treatment options, can

lead tomedicationerrors, suboptimalmanagement and result

in increased morbidity, mortality, prolonged hospitalisation

and costs. Accurate collection and documentation of drug

allergy history is essential to minimise the risk of serious

medication errors.

Aim:

• To develop a drug allergy app that will guide drug

allergy history taking and documentation and serve

as an educational platform that encourages safe

medical practice and reinforce best practice.

• The classification generated by the app is based on

the NICE clinical guidance [183] on the diagnosis and

management of drug allergies.

Objectives:

• To evaluate the accuracy of penicillin allergy history

documentation at the Trust and whether current

practice is in line with NICE clinical guidance 183.

• To assess prescribers knowledge of penicillin allergy

diagnosis and management

• To Identify prescribers views on best practice

• Toexplorepracticalaspectsofimplementingade-labelling

pathway in an NHS hospital Results and discussion:

We found that inappropriate penicillin allergy labelling

(In-PenA) is related to many factors, these included:

knowledge gaps, lack of training in allergy medicine amongst

healthcare professionals and errors in documentation. In-

PenA may subsequently increase the risk of multi-resistant

microorganisms such as Methicillin Resistant Staphylococcus

aureus (MRSA) and Clostridium difficile (C diff). The algorithm

has the lowest risk for misclassification of outcomes with a

high NPV (100%) and sensitivity (100%) with good PPV (95%)

and Specificity (96%) on the retrospective validation. It is

currently undergoing prospective validation with favourable

outcome.

Conclusion:

The drug allergy App may revolutionise the

prescribers approach to patients with a penicillin allergy

label. From our survey of prescribers; there was an obvious

tendency to adopt an over-cautious approach to prescribing

alternative beta-lactams in patients with reported penicillin

allergy.

e

:

shuayb.elkhalifa@srft.nhs.uk

Journal of Infectious Diseases and Medical Microbiology | Volume 3

Notes: