spring-dermatology-skin-care- 2018-abstracts

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Page 70
alliedacademies
Journal of Dermatology Research and Skin Care | Volume 2
May 14-15, 2018 | Montreal, Canada
Spring Dermatology &
Skin Care Expo Conference
Background: Psoriasis is associated with multiple other
comorbidities, including gastrointestinal tract (GIT) and liver
diseases (LD). But no study has been performed in Russian
population of Psoriasis (PsO) patients.
Objectives: To evaluate the prevalence of GIT and LD
comorbidity in a hospital-based cohort of patients (pts) with
severe PsO.
Methods: 330 pts (234 Male (M)/96 Female (F)), mean age
39.9±0.9/38.05±1.3 years accordingly, mean PASI 49.4±0.56,
PsO duration 11.6±0.6 years were included. PsO pts with
GIT and LD, including diseases of oesophagus, stomach
and duodenum (K20–K31), disorders of gallbladder, biliary
tract and pancreas (K80–K87), alcoholic and toxic liver
disease (K70–K77) (LD), viral hepatitis (B15–B19) (VH) were
identify in the hospital database reporting and coding by
International Statistical Classification of Disease and Related
Health Problems (ICD-10) between 2010-2011 years. M±m,
t-test, (%) were calculated. All p<0.05 were considered to
indicate statistical significance.
Results: 166 (103-M/63 - F) out of 330 pts (50.3%) had GIT
and LD. M and F pts were at the same age. No significantly
differences were found in the prevalence of GIT and LD
coding as K20–K31 betweenMand F pts – in 47 out of 103 pts
(45.6%) and in 29 out of 63 pts (46.0%) accordingly (p<0.05).
GIT and LD coding as K80–K87 were found in significantly
more cases in M pts compare to F pts - in 23 out of 103 pts
(22.3%) and in 23 out of 63 pts (36.5%) accordingly (p<0.05).
LD coding as K70–K77 were found in significantly more cases
in M pts compare to F pts - in 19 out of 103 pts (18.4%) and
in 3 out of 63 pts (4.8%) accordingly (p<0.05). VH coding as
B15–B19 were found in significantly more cases in M pts
compare to F pts - in 29 out of 103 pts (28.2%) and in eight
out of 63 pts (12.7%) accordingly (p<0.05).
Conclusions: GIT and LD comorbidities are common for
hospital-treated cohort pts with severe plaque PsO. Young
M pts with severe plaque PsO significantly often suffer from
LD and VH compared to F pts. Young F pts with severe plaque
PsO tend to suffer from diseases of the gallbladder, biliary
tract and pancreas compared to M pts.
e:
Diseases of the digestive system in young patients with severe plaque psoriasis: A hospital-based study
Nadezhda Batkaeva
Peoples’ Friendship University of Russia, Russia