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Journal of Agricultural Science and Botany | Volume: 2
November 15-16, 2018 | Paris, France
Plant Science
Natural Products,Medicinal Plants and Traditional Medicines
International Conference on
Joint Event
&
Study of antihyperglycemic, antihyperlipidemic and antioxidant activities of tannins extracted from
Warionia saharae Benth. & Coss
Mohamed Eddouks
Moulay Ismail University, Morocco
Warionia saharae Benth & Coss, a plant belonging to
Asteraceae family, is used for its anti-diabetic properties
in Morocco. The objective of this study was to evaluate
the effect of tannins extracted from Warionia saharae (W.
saharae) on blood glucose levels and lipid profile in normal
and streptozotocin(STZ)-induced diabetic rats. Tannins (TE)
were extracted from W. saharae using Soxhlet apparatus and
different organic solvents. Single and once daily repeated oral
administrationofTE(10mg/kg)for15dayswereusedtoevaluate
the glucose and lipid lowering activity in normal and diabetic
rats. Furthermore, glucose test tolerance, liver histopathological
examination and in vitro antioxidant activity of TE were carried
out in this study. The results showed that TE was able to exert
antihyperglycemic and lowering total cholesterol effects as
well as improvement of the high density lipoprotein (HDL)-
cholesterol serumlevel after 15daysof treatment. Furthermore,
TE improved glucose tolerance, histopathological status of
liver in diabetic rats and demonstrated interesting antioxidant
activity. In conclusion, the present investigation revealed that TE
possesses potent antidiabetic and antihyperlipidemic activities
as claimed in different ethnopharmacological practices.
e:
Plant science & Natural Medicine 2018, Volume 2
DOI: 10.4066/2591-7897-C1-003