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July 05-06, 2019 | Paris, France
Pharmaceutics and Advanced Drug Delivery Systems
2
nd
International Conference and Exhibition on
Asian Journal of Biomedical and Pharmaceutical Sciences | ISSN:2249-622X | Volume 9
Notes:
Effect of electrostatics on pharmaceutical powders
Bodhi Chaudhuri
University of Connecticut, USA
E
lectrostatic charging via tribocharging refers to the
process of charging or electrification of two solid surfaces
brought into contact and separated. In pharmaceutical
manufacturing and other powder handling processes,
particle charging is often a nuisance and can cause problems
during manufacturing such as poor powder flow, jamming,
segregation, dose inhomogeneity and even dust explosion. In
thisproject,systematicexperimentsandmulti-scale(quantum,
particle, device scale) numerical models are performed to
develop a unified theory of the relation of particle size, work
function difference, and surface water adsorption to the
electrostatic charging and flow behavior in granular materials.
Bipolar charging is also investigated, which is a special class
of tribocharging where granular materials procure two
opposite polarities on different sized particles of the same
material. This is vital to better understand the fundamentals
of granular tribocharging and apply the derived rules to better
design and optimize the powder handling equipment used in
pharmaceutical industry.
e
:
bodhi.chaudhuri@uconn.eduAsian J Biomed Pharmaceut Sci, | ISSN: 2249-622X
Volume 9