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O c t o b e r 1 9 - 2 0 , 2 0 1 8 | T o k y o , J a p a n
Pharma Congress 2018 & Molecular Medicine 2018
& Psychiatric Disorders 2018
Asian Journal of Biomedical and Pharmaceutical Sciences
|
ISSN: 2249-622X
|
Volume 8
International Conference on
PHARMACEUTICS AND NOVEL DRUG DELIVERY SYSTEMS
19
th
International Conference on
CELLULAR AND MOLECULAR MEDICINE
19
th
Annual Congress on
PSYCHIATRY AND PSYCHIATRIC DISORDERS
&
&
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
alliedacademies.comYEARS
Asian J Biomed Pharmaceut Sci 2018, Volume 8 | DOI: 10.4066/2249-622X-C3-009
TOWARD-ANTI-AGING AND LONG-LIFE SYNTHESIS OF ANTI-AGING
REAGENTS SULFO DISACCHARIDES CO-WORKING WITH KLOTHO (ANTI-
AGING GENE)
Showchiro Ozaki
Brain Science Institute, Japan
N
abeshima found Klotho (anti-aging gene) and sulfo disaccharide, co-working with Klotho. Ozaki synthesized several disaccha-
rides and found the structure and the mechanism how these compounds are working. The disaccharide has glucosamine struc-
tures and similar structure with hyaluronic acids and chondroitin. Klotho makes disaccharides (glucronosyll (1-3) (N-acetyl glucos-
amine. From glucosamine and glucuronic acid and co-works on site with produced disaccharide and gives stable Ca homeostasis
and consequent health, anti-aging and long life. Glucosamine, hyaluronic acid, chondroitin is now used as health food by many
persons in Japan. The author will explain how hyaluronic acid, glucosamine, chondroitin is contributing to the health and anti-aging
and long life. Japanese can live longest. Men 80.50 (third), women 86.63 (top). The reason of long life is Japanese eat many fish as
protein source. Fish contain much hyaluronic acid, glucosamine and chondroitin, which precursor of anti-aging reagents. Fish pro-
duction of Japan decreased remarkably to 10% since governments of developed country set up very strict law to eliminate NOx and
NP in waste water. The author is proposing methods to control global warming by stopping NOx, NP in waste water elimination, we
can increase the NP concentration of sea water. And we can increase plankton CO
2
fix, and we can protect global warming. And we
can get many fish and we can enjoy long life.