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O c t o b e r 1 9 - 2 0 , 2 0 1 8 | T o k y o , J a p a n
Pharma Congress 2018 & Molecular Medicine 2018
& Psychiatric Disorders 2018
Asian Journal of Biomedical and Pharmaceutical Sciences
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ISSN: 2249-622X
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Volume 8
International Conference on
PHARMACEUTICS AND NOVEL DRUG DELIVERY SYSTEMS
19
th
International Conference on
CELLULAR AND MOLECULAR MEDICINE
19
th
Annual Congress on
PSYCHIATRY AND PSYCHIATRIC DISORDERS
&
&
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
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Asian J Biomed Pharmaceut Sci 2018, Volume 8 | DOI: 10.4066/2249-622X-C3-009
MOLECULAR PROFILING AND PERSONALIZED MEDICINE OF NON-SMALL
CELL LUNG CANCER AND COLORECTAL CANCER
Dongfeng Tan
University of Texas, USA
P
ersonalized medicine, in concert with targeted oncologic therapy, has become one of the most active, rapidly advancing, and
clinically challenging pursuits in cancer treatment. A major concern for molecular geneticists and clinicians must be to focus
upon prioritizing those issues that are most important for research and targeted management in these most prolific days of cancer
medicine. In no area of medicine is this more apparent than in cancer medicine, where arrays of specific genetic alterations have
been used to manage various types of malignancies. The discoveries that form our understanding of cancer have substantially ac-
celerated over the past decade. These emerging findings have significantly affected the traditional practice of oncology and have
resulted in a subspecialized multidisciplinary approach to patient care that incorporates personalized therapies such as targeted
molecular therapy, prognosis, risk assessment, and prevention, all of which are primarily based on molecular diagnostics and im-
aging. This presentation, using non-small cell lung cancer and colorectal cancer as models, updates readers on recently acquired
knowledge of molecular pathology and emphasizes new uses for that knowledge in the changing landscape of specialized multi-
disciplinary care and personalized medicine. Novel therapeutic agents against specific genetic, molecular, and antigenic targets
are discussed, as is the process for deciding whether to use these agents. Furthermore, recent developments in targeting cancer
stem cell to avoid drug resistance, recurrence and metastasis are to be discussed.