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Journal of Medical Oncology & Therapeutics | Volume 4
March 18-19, 2019 | London, UK
Oncology & Cancer Therapy
International Conference on
Measles virus is associated with classic Hodgkin lymphoma and additional cancers - A never ending saga
Daniel Benharroch
Soroka University Medical Center and Ben Gurion University of the Negev, Israel
T
he suggestion of a relationship between the measles
virus and classic Hodgkin lymphoma was first presented
by our laboratory in 2003. Four years later, our hypothesis
was refuted conjointly by two European groups. However,
our reevaluation of the proposed arguments allowed
us to carry on with our line of research. By that time, we
submitted evidence of associations between the measles
virus and several further solid tumors, including lung
and breast cancers. Modulation of apoptosis was later
proposed as a possible mechanism in the oncogenesis of
classic Hodgkin lymphoma. Measles virotherapy has been
excluded from our discussion. Additional evidence has been
compiled in the form of Western blots of lung cancers, and
of a tissue micro-array in four categories of cancer. The
possible role of atypical measles syndrome in cancer, which
although a rare condition, but still prevalent, is discussed
in the context of immune waning. Since measles virus and
EBV expression were displayed in various combinations, we
raise the possibility that their net consequences on tumor
cell apoptosis in classic Hodgkin lymphoma, might originate
from opposing effects from the two viruses.
Speaker Biography
Daniel Benharroch started his career as an Intern at the Soroka University Medical Center
in Isreal in the year 1976. Post his internship, he worked as a resident at the Soroka
University Medical Center for several years. Over his career he has been a member of
various associations like The Israel Medical Association, The Israel Society of Pathology, The
International Academy of Pathology, The European Association of Cancer Research, The
Israel Association of Hematology, The European Hematology Association. He also served as
a member of Editorial Boeard or reviewer for journals of Clinico-Pathological Conferences
in “Harefuah”, Leukemia & Lymphoma, Acta Hematologica, The Indian Journal of Cancer.
He has taught various courses in numerous universities and is currently serving as a Full
Professor of Pathology at The Ben-Gurion University of the Negev in Israel.
e
:
benaroch@bgu.ac.il