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allied
academies
Journal of Medical Oncology & Therapeutics | Volume 4
March 18-19, 2019 | London, UK
Oncology & Cancer Therapy
International Conference on
The value of contrast enhanced ultrasound in the location of sentinel lymph node in breast cancer
Luo Jun
Sichuan Provisional People’s Hospital, China
S
entinel lymph node (SLN) location and biopsy was
designed to minimize side effects of axillary dissection
with equivalent outcomes.
Objective
: To explore the detection rate and the accuracy of
sentinel lymph node (SLN) in breast cancer by percutaneous
injection of ultrasound contrast agent in mammary areola
region.
Methods
: 400 breast cancer patients in our breast surgery
department fromJuly 2017 toNovember 2018were involved, all
patientswithpreoperative contrast-enhancedultrasound (CEUS),
that respectively intracutaneous injection ultrasonic contrast
agent 1ml at 3,6 o ‘clock and subcutaneous injection ultrasonic
contrast agent 1ml at 9, 12 o ‘clock. Tracing enhanced SLNs along
the enhanced lymphatic vessels from mammary areola after
massage for one minute. Recording the number of enhanced
SLN and marking the first SLN with injecting nanocarbon into
the SLN under the guidance of CEUS. Intraoperative dyemethod
(methyleneblue)was used to track SLNs and compare the results
with CEUS.
Results
: 395 of 400 patients with breast cancer injected
with ultrasound contrast agents had detected a total of
818 enhanced SLNs (range 1-5, 2.045±1.139), the detection
rate is 98.75%. In the 395 cases, 386 cases’ first SLNs
with the location of the CEUS matched with the first SLNs
observed in the intraoperative dye method, the accuracy is
97.72%. There were 5 patients who were found interrupted
lymphatic vessel and no enhanced SLN in CEUS. 3 of them,
whose pathological results of axillary lymph node dissection
showed that axillary lymph nodes with cancer metastasis,
observed interrupted lymphatic vessel and no dyeing lymph
node in the intraoperative dye method. While 2 of the 5
patients observed dyeing lymph nodes along the dyeing
lymphatic vessels in the intraoperative dye method, and
they didn’t metastasis.
Conclusion
: Percutaneous injection of ultrasound contrast
agent in mammary areola region has certain application
value to detect and locate the SLNs in breast cancer patient.
e:
milton-lj@hotmail.comNotes: