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Journal of Medical Oncology & Therapeutics | Volume 4
March 18-19, 2019 | London, UK
Oncology & Cancer Therapy
International Conference on
Prognostic factors for surgical outcome and survival in women treated for borderline ovarian tumors
Mohamed Zakaria Sayer Dayer
Menoufia University, Egypt
D
ata of 92 patients diagnosed with borderline ovarian
tumours (BOTs) during the period from 2010 to 2017 in
the National Cancer Institute (NCI), Cairo University, Egypt
were retrospectively evaluated, Median follow up period
was 42 months. The mean age at diagnosis was 42.7 yrs.
Histopathology was serous in 63%, mucinous in 28.3%, and
endometrioid in 3.3%. 65 patients (70.7%) had Stage IA disease,
17 patients had Stage IB disease (18.5%), 4 patients had Stage
IC disease (4.3%), 2 patients had Stage II disease (2.2%) and 4
patients had Stage III disease (4.3%) at diagnosis. 49 patients
(53.3%) underwent fertility sparing surgery, of which 19 patients
underwent Unilateral ovarian cystectomy, 5 patients underwent
Bilateral ovarian cystectomy, 25 underwent Unilateral salpingo-
oopherectomy.43 patients (46.7%) underwent radical surgery
including hysterectomy, bilateral salpingo-oopherectomy.39
patients had micropapillary disease (42 %) and 2 patients had
microinvasive disease (2.2%) on histopathology.6 patients (6.5
%) had peritoneal implants of which 1 was invasive and 5 were
non-invasive. Recurrence rate in the entire study group was
18.5%, 17.6% among patients underwent radical surgery and
82.4% among patients underwent fertility sparing surgery.12
of the recurrences (70.6%) were borderline whereas 5 were
invasive (29.4%).Stages IAand IBhad significantly higher disease
free survival than other stages. Patients withmicro invasion had
significantly lower disease free survival 10.5 (9.52 – 11.5) Vs77.6
(70.9 – 84.1). Radical surgery had significantly higher DFS than
fertility sparing surgery 75.8 (70.2 – 81.4) Vs 68.5(58.2 – 78.8).
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