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Volume 2, Issue 3 2017
Journal of Medical Oncology and Therapeutics
Dermatologists & Melanoma 2017
August 31-September 01, 2017
Page 75
&
2
nd
Euro-Global Congress on
August 31-September 01, 2017 London, UK
12
th
Global Dermatologists Congress
Melanoma and Skin Diseases
J Med Oncl Ther 2017, 2:3
Primary cutaneous follicular lymphoma associated with
Helicobacter pylori
infection
A H Bashir
1,6
, S M Yousif
2
, Lamyaa A M El Hassan
3
, W M Elamin
4
, Ameera Adam
5
, M E Ibrahim
5
, K O Alfarouk
5,6
, A K Muddathir
5
and
A M El Hassan
5
1
Khartoum College of Medical Sciences, Sudan
2
Aliaa Medical Centre, Sudan
3
Ahfad University for Women, Sudan
4
Alzaeim Alazhari University, Sudan
5
University of Khartoum, Sudan
6
H Alfarouk Cancer Center, Sudan
A
66 year old male with a long standing uncontrolled gastric
H. pylori
infection and Crohn’s disease presented with nodular
lesions in the back. These were removed surgically. Pathologically the lesion consisted of lymphocytes, giant cells with
vacuolated cytoplasm and histiocytes and immunohistochemistry analysis showed that there were stem cells, B cells and CD1a
Langerhans cells. The diagnosis of Langerhans histiocytosis was made. The giant cells were positive for both CD 20 B cell marker
and the macrophage marker CD 68 indicating that they were derived from B cells. They were strongly positive for
H. pylori
antigen. A year later the patient reported with non-itching nodular lesions in the right flank. There was no lymphadenopathy
or splenomegaly. A biopsy of the lesion showed a follicular center B cell lymphoma. The tumor cells were positive for
H. pylori
antigen. He was treated for
H. pylori
infection. He completely recovered and was in good health a year later.
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