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International Journal of Respiratory Medicine

|

Volume 3

LUNG CANCER AND COPD

5

th

International Congress on

J u n e 2 5 - 2 6 , 2 0 1 8 | A m s t e r d a m , N e t h e r l a n d s

Varuna Jethani et al., Int J Respir Med 2018, Volume 3

EFFICACY OF PLEURAL BRUSH

CYTOLOGY IN DIAGNOSIS OF PLEURAL

DISEASES

Varuna Jethani, Girish Sindhwani, Rakhee

Khanduri, Sanjeev Kumar

and

Smita Chandra

Himalayan Institute of Medical Science, India

Introduction:

Medical thoracoscopy has an established role in the achieving

etiology of pleural effusion. Thoracoscopic guided pleural biopsy though

provides good yield but is limited by a delay of three to five days. We, in this

study, used pleural brushings obtained by using bronchoscopy brush through

the working channel of rigid thoracoscopy. The hypothesis was that cytology

gives earlier results and if the results of cytology are concordant with pleural

biopsy, it may help early institution of therapy.

Aims & Objectives:

The aim of this study is to access feasibility of brush

smear from parietal pleura during thoracoscopy and to study efficacy of

pleural brushing by comparing its cytology with pleural biopsy.

Material & Methods:

All consecutive patients of undiagnosed pleural effusion

by routine investigations of pleural fluid, who were subjected to medical

thoracoscopy during the period between Dec2015 to June 2017 were included

in the study. After informed consent, brush smears and pleural biopsies were

obtained from the suspected sites of parietal pleura during thoracoscopy.

The results of cytology of brush smears were assessed and compared with

results of pleural biopsy.

Results:

45 patients were recruited during the study period of 1.5 years, mean

age was 59.68 years. Nodule was the most common finding on thoracoscopic

examination. Brush cytology report when compared to that of pleural biopsy

the concordance was seen in 80%, which is highly significant. Detail study will

be presented

Varuna Jethani has done her post-graduation in

pulmonary medicine from Swami Rama Hima-

layan University, Jollygrant Dehradun. Now She

is working as Assistant Professor in pulmonary

medicine department in same university. She

has 10 publications in reputed journals. She is

editorial board member of EC pulmonary and

Respiratory Medicine .

Varuna1212@rediffmail.com

BIOGRAPHY